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u23673660012154
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První3293366001215283134189212
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a23073940012148
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kalciového2810394001214797122168192248296346402458
kanálu3288394001214798154203227283
nebo35913940012155107165221
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diuretika.1022408001215680135169219254277325375397
V14394080012155
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cílových237040800121456895150198250295350
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krevního3075408001214782132181238262320376
tlaku3470408001213357106154210
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nasazení13994220012155104145195239290347371
fixní1799422001213057104161185
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inhibitoru2661422001212380136160218242276332365422
RAAS,31124220012154118183234255
blokátoru3397422001215782138186237270325359415
kalciového340436001214797122167191247296346403459
kanálu822436001214797154203227283
a11284360012148
nethiazidového12004360012155107141197222270315339397453501551608664
diuretika.1888436001215680136169220255279326376399
Tato2310436001215092126181
fixní2515436001212956104161185
trojkombinace2723436001213367122147195250334392417473522568618
vede3364436001214898157208
k35954360012147
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tlaku1727450001213357106154210
u19644500012155
více2047450001214873119169
než22434500012155107151
9024224500012151104
%25544500012179
hypertoniků.26604500012156102161213247284339396420467524545
Prezentovaná3232450001215486137182233289323378426475531580
kazuistika340464001214797142198222262297321368419
ukazuje7824640012155103153197253278329
možnosti11354640012183139182239295335370394
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léčby.2738464001212375121179226243
Klíčová340481001246190118163221273326
slova:686481001244472131183236261
arteriální969481001214881117166199222270294349372
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kazuistika.2852481001214796139194218257291314360409431
Uncompensated3405090012468127173230317377431491534588625678739
64-year‑old10995090012456113149201253306345377438466527
hypertensive16465090012458109170224263302355415459487540592
patient22585090012460113150179232292328
with26065090012476104141201
acute2828509001245298157194248
MI30965090012484114
The3405260012150106157
Czech5195260012158103153199254
Republic7965260012154104161217273297320365
is1184526001212363
one12695260012155111161
of1453526001215584
the1560526001213389139
countries1722526001214598154209241274297348387
with2132526001217497130186
a23405260012149
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risk259054000121335695142
factor.2758540001212978123158212245262
Hypertension30465400012165112170221254290339395434457512568
prevalence3640540001215689139340554001214895118168223267315
in672554001212378
the767554001213387137
Czech9215540012157101151195250
Republic11885540012153103159214270293315359
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40%22545540012151103182
of2453554001215483
the2553554001213387137
adult27075540012148103157180212
population.29375540012156111167222245292324346401455476
However,34305540012165120191240287335367383
target340568001213382114170220254
blood622568001215681136191249
pressure898568001215790140179219273306355
values1281568001214897120175225265
or1573568001215588
reduction1689568001213382140194239275298353408
of2125568001215584
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cardiovascular2544568001214493126182205260307356395440495518566599
risk317056800121335696142
are3340568001214881130
still349856800121407497120143
not36695680012155110143
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by7355820012157104
the859582001213388138
majority10175820012184132156211244267300350
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those1491582001213388143183233
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The20885820012149106156
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guidelines25875820012156111134191241265288343394433
for3040582001212984117
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high3623582001215578134189
blood340596001215781136192249
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and9955960012149104160
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hypertension15015960012155101158209242278327383422445500556
now20825960012156111184
recommend2292596001213282128182265348399455511
a28295960012148
target2903596001213382114170220254
blood3182596001215781136192249
pressure3457596001215790140179218273305355
of340610001215584
120442610001215195146
-6066100012130
129654610001215296146
mmHg8186100012183166232288
systolic1124610001214088128162216240263307
blood1449610001215781136192249
pressure1716610001215790140179219273306355
within2089610001217498131186209264
three2371610001213388121171222
months26116100012183138194226281320
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treatment3394610001213466116164197280330386418
for340624001212984116
most4746240012183137176210
hypertensive7016240012155100157208241276325380419441489538
patients.12566240012157105137160210265297337358
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of2454624001215584
antihypertensive25556240012148103135158212257315365398433482537576598646695
drugs3267624001215689144199238
remain3522624001213382165213236290
the340638001213388139
gold5046380012156111135191
standard721638001213973122177234282314371
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treatment.1226638001213366115163196279330385418439
It1690638001212457
is1772638001212463
their1860638001213388139162194
much20806380012183138183238
wider2343638001217497154204237
use2605638001215595145
in2775638001212479
everyday2879638001215098147180230286334379
practice3283638001215790139184219242287336
that3644638001213388136169
may3406520012183131177
be5436520012157108
the678652001213388138
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to1094652001213387
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target1638652001213382114170220254
blood1918652001215781136192249
pressure2193652001215790140179219273305355
values2575652001214896120174225264
in2865652001212479
most29706520012184139178212
hypertensives.32086520012156101159210243279328384423446494543583604
The3406660012150106157
first51966600121295588128162
choice704666001214499154178223272
for998666001212984117
most11386660012183138178212
patients13726660012157106138161211267299340
should1734666001214095150206229286
be20426660012157108
a21736660012148
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two-dose24746660012133109163197256311350401
combination2897666001214599182239263318366398421476532
of3452666001215584
a35586660012148
lowdose36296660012123791513406800012156112151201
RAAS5676800012153116180230
(renin-angiotensin-aldosterone8226800012128581081641872422743223784344575125455946506897117677998478709279821021105511041137119212481298
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inhibitor2490680001212479134157214237271325357
and28736800012148103160
a30586800012148
calcium3132680001214493117162184239322
channel3480680001214499147203258308332
blocker340694001215882139185232282316
or685694001215689
non-thiazide8036940012157113169202236293316365409433491542
diuretic.1374694001215881137170221255279324347
If1750694001212454
target1833694001213484117174225259
blood2121694001215883139195254
pressure2404694001215891142182222278311362
values2795694001214998122178229269
are3093694001214982133
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achieved3430694001214995151175226274324383
within340708001217497130186209264
three631708001213388120170221
months,8797080012183138194226281320342
a12477080012149
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triple155770800121336689146170220
combination1804708001214599182239263318366398421476532
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RAAS24747080012153116180230
inhibitor,2730708001212479134157214238271325358374
calcium3131708001214493116161184239322
channel34807080012145100148203258309333
blocker,340722001215781136182228277310326
and6877220012148103160
non-thiazide8687220012155110166198231287310358401424481531
diuretic1420722001215780134167217250273318
is1759722001212362
indicated.1842722001212379135158203252284334391412
This22757220012149106129168
fixed2464722001212955102151208
triple269372200121336689146170220
combination2934722001214598182239262318366398421476532
leads3487722001212374122178218
to3726722001213387
achieving340736001214891145167216263286340395
target751736001213381112167216248
blood1016736001215680133188244
pressure1277736001215688136175213266298346
values1640736001214795117171220258
in1915736001212377
more20097360012182136168217
than2243736001213286133187
90%24477360012150101180
of2644736001215482
hypertensive2743736001215499155205237272320374412435482530
patients.32897360012157104136158207261293332353
The36597360012149104153
presented340750001215689138177226281313362418
case775750001214593131181
report973750001213382138193225261
demonstrates12517500012156105188242297336369401449481529568
the1836750001213387137
potential19907500012157112144193248279302349372
of2379750001215583
fixed2480750001212954100148205
triple270275000121336588144167217
combination2936750001214598180236259314361393415470525
therapy.3478750001213387137169217273318334
Key3407670012461113164
words:5257670012475133171232276302
arterial848767001214881117166199222270294
hypertension,11637670012155101159210243278328383422445500556577
treatment,1761767001213366115163196279330385418439
fixed2221767001212955102151208
combination,2451767001214498182238262317365398421476532552
case3024767001214594133184
report.3229767001213282139195228264285
DECLARATIONS:4070243008648871301662142563043393604124625014571243008514
Declaration406925600874987120141179207245272292334376
of445925600874166
originality:45392560087406888131151193231252272299338358
The406926800853473109
manuscript418926800855791130168195227249266306329
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and481726800853472112
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been516226800853975110149
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or406927900853862
submitted414627900852867108167184208234269310
elsewhere.44712790085355381117169209246269305320
Ethical406929200873764107127160198219
principles43022920087427090132165185229249288319
compliance:463629200873172134177198218256298331369388
The406930300853678116
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attest44653030085356087124154179
that466530300852465101126
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Committee464931400854179139198215239265300337
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regulations53913250085236110414516420140693360085234080120148
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authors’44353360085347397136176200229244
institutions46993360085165684109126150189214231270310338
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