Med. praxi. 2010;7(2):69-73

Specifics of Peripheral Vascular Disease by the diabetics

MUDr.Jarmila Indráková

I. interní klinika a II. chirurgická klinika LF UP a FN Olomouc

Peripheral Vascular Disease (PVD) affects estimatedly up to 20 % of the patients over 70 years. In its less advanced stages (stage I and II of the

Fontain classification) is chiefly a predictor of increased cardiovascular mortality due to a high probability of collateral ischemic heart and

brain disease. The more advanced stages of the disease limit the prognostically ill person significantly and they principally threaten the

quality of life, not only by the possibly amputation of the limb. There is 5 times more risk of PVD and possibility of gangrene 20 times

more in diabetic patients than in nondiabetic patiens. Incidence of PVD in population of diabetic patiens is almoust 30 %. Approximately

40–60 % of untraumatic amputations is provided in diabetic pationts. Diabetic foot syndrom has up to 6 % of patients with diabetes. That

is why the good compensation of diabetes is implied. Pharmacotheraphy is necessary – antiplatelet drugs, hypolipidemics, ACE inhibitors

and vasoactive drugs. The prostaglandines are reserved for the critical limb ischemia. As for the non pharmacologic means intensive

rehabilitation, good care of feet or diabetic footwear is required. In the cases of significant manifestations of the disease (stage III and IV

of the Fontain classification) the revascularisation, e. g. percutaneous transluminal angioplasty or surgical operations (endarterectomy,

bypasses) is unambiguously preferred.

Keywords: peripheral arthery disease, diabetes mellitus, atherosclerosis, diabetic foot

Published: April 22, 2010  Show citation