Med. praxi. 2011;8(4):156-159

Current treatment of essential arterial hypertension

MUDr.Filip Málek, Ph.D., MBA

Kardiovaskulární centrum, Nemocnice Na Homolce, 3. LF UK, Praha

The efficacy of antihypertensive therapy on cardiovascular mortality and morbidity is based on the effect on blood pressure lowering.

Effective decrease of blood pressure is provided by: thiazide diuretics, beta-blockers, calcium channel blockers, angiotensin-converting

enzyme inhibitors and angiotensin receptor blockers. These drugs represent the treatment of choice either for monotherapy, or for the

combination. Pharmacotherapy of hypertension is guided either by blood pressure level, the presence of associated clinical condition, the

severity of target organ damage and the total cardiovascular risk. Up-to now, there is no evidence of the treatment benefit in the management

of high normal blood pressure. The choice of the treatment drug group depends on the type of the associated clinical condition.

hypertension crisis.

Keywords: arterial hypertension, pharmacotherapy, guidelines, target values, cardiovascular risk, combination therapy, resistant hypertension,

Published: May 1, 2011  Show citation