Med. praxi. 2011;8(12):548-551
Acute phosphate nehropathy as the complication of bowel cleansing for colonoscopy.
- 1 II. interní klinika FN Královské Vinohrady, Praha
- 2 l. interní klinika 3. LF UK a FN Královské Vinohrady, Praha
- 3 Ústav patologie, FN Královské Vinohrady, Praha
- 4 Ústavní lékárna FN Královské Vinohrady, Praha
We describe case of patient which developed a high level of serum kreatinin, after phosphate administration for bowel cleansing before
coloscopy and irigography. Normal urine volume and frequency was observed. Renal biopsy showed acute phosphate tubular nephropathy.
After 6 months due to dehydration high serum kreatinin level appeared again and patients was introduced into chronic haemodialysis
program. The authors point to danger of phosphate cleansing bowel solution before endoscopy and radiography in patients with stones
or infection of urinary tract, diabetes mellitus and using drug influencing calcium phosphate metabolism etc. This nephropathy leads in
all cases in chronic renal insuficiency of different grading including hemodialysis or kidney transplantation. In above mentioned cases
the authors prefer macrogol solutions for bowel cleansing.
Keywords: acute phosphate nephropathy, renal insuficiency, large bowel cleansing, colonoscopy, dehydration
Published: December 15, 2011 Show citation
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