Med. praxi. 2012;9(2):48-52

Is prevention of cardiovascular events a question of the treatment chosen?

MUDr.Michal Vrablík, Ph.D.

Centrum preventivní kardiologie, III. interní klinika 1. LF UK a VFN, Praha

There are increasing options of intervention on risk factors for atherosclerosis (and cardiovascular diseases). However, it is apparent that

not all methods of modifying the risk profile have the same effect on the occurrence of clinical episodes. The success of an intervention is

determined by correct timing, the decision on the method of treatment, the selection of a particular treatment strategy as well as patient

compliance with the proposed strategies. In most clinical settings today, antihypertensive regimens based on a combination of a RAS

blocker and a calcium channel blocker usually combined with hypolipidaemic statin treatment are well established as the cornerstones

of pharmacotherapy to reduce cardiovascular risk. This strategy with an established synergistic effect certainly is not universal, but may

well be suitable for a large group of patients in primary as well as secondary prevention of circulatory complications.

Keywords: cardiovascular risk, arterial hypertension, dyslipidaemia, RAS blockade, statins, compliance

Published: February 23, 2012  Show citation