Med. praxi. 2012;9(2):75-78

Erectile dysfunction - diagnosis, new treatment preferences

MUDr.Taťána Šrámková, CSc.

Klinika traumatologie LF Masarykovy univerzity, Úrazová nemocnice, Brno

Urologická klinika 1. LF UK a VFN, Praha

Erectile dysfunction is defined as an inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse. Erectile

dysfunction (ED) and coronary artery disease (CAD) have the same morphological base – endothelial dysfunction as a first stage of

atherosclerosis. ED and CAD have the same risk factors, as a hypertension, dyslipidemia, diabetes mellitus, obesity, age, smoking and

sedentary lifestyle. The time interval among the onset ED symptoms and the occurence of CAD symptoms and cardiovascular events

is estimated at 2–3 years and 3–5 years respectively. Modern oral form of ED therapy by PDE5 inhibitors is safe and effective and is well

tolerated. The second step is using intracavernous pharmacotherapy by PGE1.

Keywords: erectile dysfunction, endothelial dysfunction, PDE 5 inhibitors, intracavernous pharmacotherapy

Published: February 23, 2012  Show citation