Med. praxi. 2012;9(10):391-394

Clostridium-difficile infection - curent state in the year 2012

MUDr.Ondřej Zela¹, MUDr.Petr Vítek^1,2

¹ Beskydské gastrocentrum, Interní oddělení Nemocnice ve Frýdku-Místku, p. o.

² Lékařská fakulta Ostravské univerzity, Ostrava

Clostridium difficile-associated diarrhea (CDAD) and pseudomembranous colitis have become a significant challenge in current clinical

medicine, posing a serious risk to any patient undergoing treatment with broad-spectrum antibiotics in either inpatient and outpatient

setting. Although CDAD still remains relatively unknown to the lay public, the number of patients at risk of developing this condition is

growing steadily. Recent treatment approaches seek to maintain normal colonic flora while effectively optimizing host immune response.

The following article presents a concise overview of up-to-date guidelines with particular emphasize on recurrent form of the disease.

fidaxomicin, fecal transplantation, vaccination.

Keywords: Clostridium-difficile associated diarrhea, pseudomembranous colitis, broad-spectrum antibiotics, vancomycin, metronidazol,

Published: November 1, 2012  Show citation