Med. praxi. 2018;15(3):167-170 [Prakt. lékáren. 2017; 13(4): 166-168]

Ergotamine-induced coronary artery spasm

Mgr. Andrea Carbolová^{1, 2}, MUDr. Jan Novák^{2, 3}

¹ Nemocniční lékárna Fakultní nemocnice u sv. Anny v Brně

² II. interní klinika Fakultní nemocnice u sv. Anny v Brně

³ Lékařská fakulta Masarykovy univerzity v Brně

For many years, ergotamine has been used for the acute treatment of migraine. In most patients, ergotamine is well tolerated,but also has potential for many side effects. It has been reported, that ergot alkaloids can provoke coronary artery spasm, whichis often associated with ischemic electrocardiography changes and angina pectoris.In the present report, we describe a case involving woman with unclear diagnosed migraine who experienced acute coronarysyndrome most probably because of therapy with ergotamine.To add the knowledge to submitted report, an information about phenomenon of egrotamine overuse headache and aboutcauses of coronary vasospasm are included.

Keywords: ergotamine, migraine, coronary artery spasm

Published: July 1, 2018  Show citation