Med. praxi. 2023;20(2):85-89 | DOI: 10.36290/med.2023.012

Therapy of diarrhea of non­‑infectious origin

PharmDr. MVDr. Vilma Vranová, Ph.D.
Ústav aplikované farmacie, Farmaceutická fakulta VFU Brno

Acute diarrhea has most commonly an infectious origin, the basis of pharmacotherapy is rehydration, diet, and optimal pharmacotherapy. With chronic diarrhea, the basis is correct diagnosis, we should not forget less common causes of diarrhea, such as side effects of drugs, irritable bowel syndrome, or adverse reactions to food. The communication is devoted to these causes, their prevention, and therapy.

Keywords: diarrhea, irritable bowel syndrome, food intolerance, loperamide, gelatin tannate.

Accepted: May 10, 2023; Published: May 10, 2023  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Vranová V. Therapy of diarrhea of non­‑infectious origin. Med. praxi. 2023;20(2):85-89. doi: 10.36290/med.2023.012.
Download citation

References

  1. Rokyta R, et al. Fyziologie a patologická fyziologie: pro klinickou praxi. 1. vydání. Praha: Grada, 2015. ISBN 978-80-247-4867-2.
  2. Kent AJ, Banks MR. Pharmacological management of diarrhea. Gastroenterol Clin North Am. 2010 Sep;39(3):495-507. doi: 10.1016/j.gtc.2010. 08. 003. PMID: 20951914. Go to original source... Go to PubMed...
  3. Riddle MS, DuPont HL, Connor BA. ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults. Am J Gastroenterol. 2016 May;111(5):602-22. doi: 10.1038/ajg.2016.126. Epub 2016 Apr 12. PMID: 27068718. Go to original source... Go to PubMed...
  4. Doporučené diagnostické a terapeutické postupy pro všeobecné praktické lékaře. Available from: https://www.svl.cz/files/files/Doporucene­‑postupy­‑od-2013/Akutni­‑prujem­‑u-dospelych.pdf.
  5. Ambrožová H. Průjmová onemocnění a jejich léčba. Prakt. lékáren. 2011;7(3):116-120.
  6. Alušík, Š. Klinické projevy nežádoucích účinků léků. Praha; Triton: 2001.
  7. Abraham B, Sellin JH. Drug­‑induced diarrhea. Curr Gastroenterol Rep. 2007 Oct;9(5):365-72. doi: 10.1007/s11894-007-0044-x. PMID: 17991336. Go to original source... Go to PubMed...
  8. Lochmannová J. Průjmová onemocnění jako vedlejší účinek farmakoterapie. Interní Med. 2011;13(9):340-342.
  9. Farmakoterapeutické informace, SÚKL, 11, 2017
  10. Historical Development of Symptom­‑Based Criteria, [Internet]. [cited 2022 May 3]. Available from https://theromefoundation.org/
  11. Seifert B, Tachecí I, Bureš J. Dráždivý tračník. Doporučený diagnostický a terapeutický postup pro všeobecné praktické lékaře 2019. Společnost všeobecného lékařství ČLS JEP. ISBN 978-80-88280-14-9.
  12. Alonso­‑Cotoner C, Abril­‑Gil M, Albert­‑Bayo M, et al. The Role of Purported Mucoprotectants in Dealing with Irritable Bowel Syndrome, Functional Diarrhea, and Other Chronic Diarrheal Disorders in Adults. Adv Ther. 2021 May;38(5): 2054-2076. Go to original source...
  13. Lopetuso L, Graziani C, Guarino A, et al. Gelatin tannate and tyndallized probiotics: a novel approach for treatment of diarrhea. Eur Rev Med Pharmacol Sci. 2017 Feb;21(4):873-883. PMID: 28272692. Go to PubMed...
  14. Bonneto S, et al. Non­‑pharmacological strategies to treat irritable bowel syndrome: 2022 update. Minerva Gastroenterology. 2022;68(4):475-481. Go to original source...
  15. Kopelentová E, Vernerová E. Potravinové alergie z pohledu alergologa. Med praxi. 2016;13(5):242-247. Go to original source...
  16. Sapone A, Bai JC, Ciacci C, et al. Spectrum of gluten­‑related disorders: consensus on new nomenclature and classification. BMC Med. 2012;10:13. Go to original source... Go to PubMed...
  17. Hoffmanová I, Sánchez D. Neceliakální glutenová senzitivita. Vnitř Lék. 2015;61(3):219-227. Go to PubMed...
  18. Fedewa A, Rao SS. Dietary fructose intolerance, fructan intolerance and FODMAPs. Curr Gastroenterol Rep. 2014 Jan;16(1):370. Go to original source...
  19. Gibson PR, Sheperd SJ. Food choice as a key management stratégy for functional gastrointestinal symptoms. Am J Gastroenterol. 2012;107(5):657-666. Go to original source...
  20. Frasca G, Cardile V, Puglia C, et al. Gelatin tannate reduces the proinflammatory effects of lipopolysaccharide in human intestinal epithelial cells. Clin Exp Gastroenterol. 2012;5:61-7. Go to original source... Go to PubMed...
  21. Juřica K, Kroupa R. Farmakoterapie dráždivého tračníku. Prakt. Lékáren. 2017;13(2):52-59. Go to original source...
  22. Bajerová K. Laktózová intolerance - praktický přístup. Pediatr. praxi. 2018;19(3):139-141. Go to original source...
  23. Vela MF, Richter JE, Pandolfino JE, et al. Refluxní Choroba jícnu - GERD. Praha: Grada Publishing; 2015.
  24. Kolář P. Rehabilitace v Klinické Praxi. Praha: Galén; 2020.
  25. Vranová V, Šopíková J. Úloha lékárníka v léčbě funkčních onemocnění GIT se zaměřením na použití rostlinných léčiv. Prakt. lékáren. 2022;18(2):110-115. Go to original source...
  26. Schmidt RF, Willis WD; editors. Somatovisceral Convergence. In: Encyclopedia of Pain. Berlin, Germany: Springer; 2007.




Medicine for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.