Med. praxi. 2025;22(5):333-337 | DOI: 10.36290/med.2025.075
Results of the Czech Myeloma group project CRAB II
- 1 IV. interní hematologická klinika, Fakultní nemocnice a Lékařská fakulta Univerzity Karlovy Hradec Králové
- 2 I. interní klinika - klinika hematologie, Všeobecná fakultní nemocnice a 1. lékařská fakulta Univerzity Karlovy Praha
Multiple myeloma is the second most common hematologic malignancy in the Czech Republic, and its incidence continues to rise. Clinical experience shows that up to half of patients with multiple myeloma begin treatment late due to delayed diagnosis. The original CRAB project by the Czech Myeloma Group was aimed at addressing this issue. The current article summarizes the results of the questionnaire phase of the CRAB II project, which is intended to be followed by a large-scale information campaign about the symptoms of the disease, including recommended diagnostic procedures when a possible connection to this serious condition is suspected. Improving the diagnosis of multiple myeloma - especially in terms of early detection - and advancing modern treatment approaches to first-line therapy should, in the future, lead to further prolongation and simultaneous improvement of patients' quality of life.
Keywords: multiple myeloma, diagnosis, CRAB project.
Received: August 11, 2025; Revised: October 14, 2025; Accepted: October 23, 2025; Published: December 1, 2025 Show citation
References
- Hájek R, Maisnar V, Minařík J, et al. Diagnostika a léčba mnohočetného myelomu. Transfuze Hematol Dnes. 2023;29(Suppl. 2):1-142.
- Rajkumar SV, Dimopoulos MA, Palumbo A, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15(12):e538-e548.
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