Onkologická onemocnění u geriatrických pacientů

prof. MUDr. Hana Matějovská Kubešová, CSc.

Med. praxi. 2021;18(5):299  

Dyslipidemias - a practical approach

MUDr. Barbora Nussbaumerová, Ph.D.

Med. praxi. 2021;18(5):303-310 | DOI: 10.36290/med.2021.051  

Dyslipidemia/hypercholesterolemia is one of the most important cardiovascular risk factors. The new Guidelines of the European Society of Cardiology and European Atherosclerosis Society recommend how to stratify and decrease the cardiovascular risk according to the evidence based medicine and how to treat dyslipidemias. The lifestyle recommendations are the cornerstone, the pharmacotherapy is mostly started with statins. Ezetimibe and biological treatment of dyslipidemia find their place.

Asthma in adulthood

MUDr. Alena Vlachová, doc. MUDr. Libor Fila, Ph.D.

Med. praxi. 2021;18(5):311-315  

Asthma bronchiale is chronic inflammatory disease with the variable picture. It is necessary to stabilize the inflammation a prevent worsening to the severe disease.

Depression in patients with cardiovascular disease - can be treated safely?

MUDr. Eva Kitzlerová, Ph.D.

Med. praxi. 2021;18(5):316-321 | DOI: 10.36290/med.2021.053  

Depressive disorder is important risk factor for onset and development of cardiovascular diseases. It must be diagnosed and treated early and adequately. Now its evident that depressive symptoms in patients with cardiovascular diseases can be treated effectively and safety and that they can decrease burden of patients with other complications. The first choice of treatment are SSRI antidepressants, but SNRI or other modern antidepressants with specific mechanisms of action can be also used. During the treatment is necessary use the safety dosage of antidepressants, think of individual risk factors for QT prolongation and severe ventricular arrhythmias...

Current recommendations on prevention and treatment of seasonal respiratory diseases

MUDr. Hana Fojtů

Med. praxi. 2021;18(5):322-326 | DOI: 10.36290/med.2021.054  

Autumn and winter months are a period of increasing rates of respiratory diseases. In 80-90 % of cases, these are viral infections with very similar symptoms; while most have an uneventful course, some may occasionally have a more severe course with complications. They are collectively referred to as acute respiratory infections (ARIs), sometimes also referred to as influenza-like illnesses (ILIs). However, in the context of the current SARS-CoV-2 pandemic, more thorough differential diagnostic considerations as well as greater emphasis on prevention are required.

Patient with angioedema - what a general practitioner should know?

MUDr. Marta Sobotková

Med. praxi. 2021;18(5):331-335 | DOI: 10.36290/med.2021.056  

Angioedema is self-limited localized subcutaneous or submucosal swelling due to enhanced vascular permeabilitity. There are two main mediators involved in angioedema pathogenesis - histamine and bradykinine. Distinguishing between histaminergic and bradykinin mediated angioedema is crucial for choosing an effective treatment.

Epilepsy in adults - a practical view

MUDr. Tomáš Nežádal, Ph.D.

Med. praxi. 2021;18(5):336-342 | DOI: 10.36290/med.2021.057  

Epilepsy is a common neurological disease with a relatively good prognosis. This article presents basic epidemiological facts, definitions and a brief overview of epilepsy etiologies. The new seizure classification was issued a few years ago. The next section is devoted to the examination and seizure differential diagnosis. The last part describes the management of therapy and patients monitoring.

Current perspective on treating lymphoedema

MUDr. Naděžda Vojáčková

Med. praxi. 2021;18(5):344-348  

Lymphoedema treatment is necessary and the sooner it is initiated, ideally at the stage of latent lymphoedema, the better are the results. The gold standard of treatment is complete decongestive therapy which includes: manual lymphatic drainage, instrumental lymphatic drainage, external compression with bandages or compression aids, supportive physical and breathing exercises, skin care, and daily routine measures. In individual cases, surgical treatment is used. Lymph taping can be employed in any treatment phase. Pharmacological treatment and psychotherapy are of a supportive nature. The purpose of complete decongestive therapy is to increase lymph...

Drug problems associated with male lower urinary tract symptoms therapy

PharmDr. Alena Pilková, PharmDr. Jan Miloslav Hartinger, Ph.D., PharmDr. Petra Hrnčířová

Med. praxi. 2021;18(5):349-354  

Male urinary tract symptoms (M-LUTS) belong to common complaints that are treated with drugs from several pharmacotherapeutic groups, with different mechanism of action, different mechanism of adverse affects and associated potential drug related problems. When choosing a suitable drug, it is necessary to assess patients´ general health status and concomitant medication, in order to minimize the risk of adverse effects in predisposed individuals. The text presented here summarizes current approach to the pharmacotherapy of M-LUTS and in several case reports demonstrates possible drug-related problems associated with this therapy.

COSYREL® - jedna fixní kombinace - rozmanité využití v praxi

MUDr. Zdeněk Coufal

Med. praxi. 2021;18(5):327-329