Med. praxi. 2011;8(6):293-297

Treatment of pain and inflammation in rheumatic diseases and the role of a general practitioner

prof.MUDr.Karel Pavelka, DrSc.
Revmatologický ústav Praha

To explain the principles of pain treatment in rheumatic diseases, the author has chosen to present the cases of four specific patients

from his practice that have been diagnosed with rheumatoid arthritis, ankylosing spondylitis, gouty arthritis and osteoarthritis. These

are the most commonly diagnosed conditions the treatment of which may be used as a model for a number of related disease entities.

The mainstay of pain treatment in rheumatoid arthritis and ankylosing spondylitis is to effectively suppress inflammatory activity, most

commonly by combining low doses of glucocorticoid, a disease-modifying antirheumatic drug (DMARD) and/or a biological agent.

When the pain persists, nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics are administered. In a gout attack, however,

NSAIDs are the first-choice drugs from the onset of disease. In osteoarthritis, nonpharmacological and pharmacological approaches

are combined. Paracetamol is the first-choice drug followed by locally and systemically administered NSAIDs and/or symptomatic slowacting

drugs in osteoarthritis (SYSADOA).

Keywords: pain, rheumatic diseases, analgesics, nonsteroidal antirheumatic drugs

Published: July 1, 2011  Show citation

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Pavelka K. Treatment of pain and inflammation in rheumatic diseases and the role of a general practitioner. Med. praxi. 2011;8(6):293-297.
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