Med. Pro Praxi 2008; 5(4): 160-163

Chronický únavový syndrom

MUDr. Martin Nouza CSc
Centrum klinické imunologie, Praha

Chronický únavový syndrom je stále, po více než 20 letech studia, předmětem kontroverzních postojů. Dnes se domníváme, že se jedná o neheterogenní skupinu stavů s různými příčinami a relativně stejným projevem a klinickým obrazem. Z této skupiny je třeba diagnosticky vyloučit příčiny s jasným původem (infekce, záněty, primárně psychické problémy) a ty kauzálně léčit. Všechny pacienty je však třeba sledovat a poskytnout jim potřebný, empatický, vysoce erudovaný přístup.

Keywords: chronický únavový syndrom, CFS, lymeská borrelióza, chlamydióza, únava, subfebrilie

Published: July 1, 2008  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Nouza M. Chronický únavový syndrom. Med. praxi. 2008;5(4):160-163.
Download citation

References

  1. Bode L, Zimmermann W, Ferszt R et al. Borna disease virus genome transcribed and expressed in psychiatric patients. Nat. Med. 1995; 1 (3): 232-236. Go to original source... Go to PubMed...
  2. Bou-Holaigah I, Rowe PC, Kan J et al. The relationship between neurally mediated hypotension and the chronic fatigue syndrome. JAMA, 1995; 274 (12): 961-967. Go to original source...
  3. Dickinson CJ. Chronic fatigue syndrome - aethiological aspects. Eur. J. Clin. Ivest. 1997; 27 (4): 257-267. Go to original source... Go to PubMed...
  4. Fučíková T, Kryštůfková O, Janatková I. Chronický únavový syndrom. Fórum Imunologie 1993; 1 (3): 93-97.
  5. Fučíková T. Klinická imunologie v praxi. Praha: Galén, 1997.
  6. Fukuda K, Straus SE, Hickie I et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann. Intern. Med. 1994; 121 (12): 953-959. Go to original source... Go to PubMed...
  7. Fukuda K, Nisenbaum R, Stewart G et al. Chronic multisymptom illness affecting Air Force veterans of the Gulf War. JAMA 1998; 280 (11): 981-988. Go to original source... Go to PubMed...
  8. Holmes GP, Kaplan JE, Gantz NM et al. Chronic fatigue syndrom: a working case definition. Ann. Intern. Med. 1988; 108 (3): 387-389. Go to original source... Go to PubMed...
  9. Cho HJ et al. Chronic fatigue syndrome: an update focusing on phenomenology and pathophysiology. Curr. Opinion. Psych. 2006; 1 (1): 67 - 73. Go to original source... Go to PubMed...
  10. Chronic fatigue syndrome. information for physicians. National institute of allergy and infectious diseases, National institutes of health, Bethesda, 1996.
  11. Chronic fatigue syndrome. Report of a joint working group of the Royal Colleges of Physicians, Psychiatrists and General Practitioners, London, 1997.
  12. Klimas NG, Koneru AO. Chronic fatigue syndrome: inflammation, immune function, and neuroendocrine interactions. Curr. Rheumatol. Rep. 2007; 1 (6): 482-487. Go to original source... Go to PubMed...
  13. Katon W, Russo J. Chronic fatigue syndrom criteria: a critique of the requirement for multiple physical complaints. Arch. Intern. Med. 1992; 152 (8): 1604-1609. Go to original source... Go to PubMed...
  14. Komaroff AL. A 56-year-old woman with chronic fatigue syndrome. JAMA 1997; 278 (14): 1179-1185. Go to original source...
  15. Komaroff AL, Fagioli LR, Geiger AM et al. An examination of the working case definition of chronic fatigue syndrome. Am. J. Med. 1996; 100 (1): 56-64. Go to original source... Go to PubMed...
  16. Litzman J, Lokaj J, Fučíková T. Chronický únavový syndrom. Čas Lék čes 1998 137 (10): 295-298. Go to original source...
  17. MacDonald K, Osterholm MT, LeDell KH et al. A case-control study to assess possible triggers and cofactors in chronic fatigue syndrome. Am. J. Med. 1996; 100 (5): 548-554. Go to original source... Go to PubMed...
  18. Mawle AC, Nisenbaum R, Dobbins JG et al. Immune responses associated with chronic fatigue syndrome: a case-control study. J Infect Dis 1997; 175 (1): 136-141. Go to original source... Go to PubMed...
  19. McKenzie R, O' Fallon A, Dale J et al. Low-dose hydrocortisone for treatment of chronic fatigue syndrome. JAMA 1998; 280 (12): 1061-1066. Go to original source... Go to PubMed...
  20. Natelson BH, Cheu J, Hill N et al. Single-blind, placebo phase-in trial of two escalating doses of selegiline in the chronic fatigue syndrome. Neuropsychobiology, 1998; 37 (3): 150 - 154. Go to original source... Go to PubMed...
  21. Nouza M. Co je a co není chronický únavový syndrom. In: Honzák R. (Ed.): Kde se stala chyba? Kazuistiky I. Praha: Galén 1997.
  22. Nouza M. Chronický únavový syndrom. In: Rovenský J. a kol. Reumatológia v teórii a praxi VI. Martin: Osveta 2004: 363-370.
  23. Nouza M, Svoboda J. Chronický únavový syndrom. Praha: Galén 1998.
  24. Peakman M, Deale A, Field R et al. Clinical improvement in chronic fatigue syndrome is not associated with lymphocyte subsets of function or activation. Clin. Immunol. Immunopathol. 1997; 82 (1): 83-91. Go to original source... Go to PubMed...
  25. Sharpe MC, Archard LC, Banatvala JE et al. A report - chronic fatigue syndrom: guidelines for research. J. R. Soc. Med. 1991; 84 (2): 118-121. Go to original source... Go to PubMed...
  26. Sheng WS, Hu S, Lamkin A et al. Susceptibility to immunologically medated fatigue in C57BL/6 versus Balb/c mice. Clin Immunol Immunopath 1996; 81 (2): 161-167. Go to original source... Go to PubMed...
  27. Steidl L, Kubíčková J, Bystroň J. Chronický únavový syndrom. Prakt. Lék. 1993; 73 (4): 134-139.
  28. Straus SE. Defining the chronic fatigue syndrome. Arch. Intern. Med. 1992; 152 (8): 1569-1570. Go to original source... Go to PubMed...
  29. Suhadolnik RJ, Peterson DL, O' Brien K et al. Biochemical evidence for a novel low molecular weight 2-5A-dependent RNase L in chronic fatigue syndrome. J. Interferon Cytokine Res. 1997; 17 (7): 377-385. Go to original source... Go to PubMed...
  30. Swanink CM, Vercoulen JH, Galama JM et al. Lymphocyte subsets, apoptosis, and cytokines in patients with chronic fatigue syndrome. J. Infect. Dis. 1996; 173 (2): 460-463. Go to original source... Go to PubMed...
  31. Šterzl I, Zamrazil V. Endokrinopatie v diferenciální diagnostice chronického únavového syndromu. Vnitř. Lék. 1996; 42 (9): 624-626.
  32. Wallace DJ. The fibromyalgie syndrome. Ann. Med. 1997; 29 (1): 9-21. Go to original source... Go to PubMed...
  33. Wessely S, Nimnuan C, Sharpe M. Functional somatic syndromes: one or many? Lancet 1999; 354 (9182): 936-939. Go to original source... Go to PubMed...




Medicine for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.