Upper dyspeptic syndrome

Dyspepsia is a group of symptoms, usually of long-term nature, that are related to digestion and localized by the patient in the area of the

digestive system. A more detailed definition and principles of approach in the practice can be found in the Society of General Practice of the

Czech Medical Association of J. E. Purkyně 2012 Guideline Update. Dyspeptic complaints are among the most common reasons for self-treatment

as well as for seeing a doctor and considerable amounts of money are spent on their diagnosis and treatment. The epidemiological

background of dyspeptic complaints has been changing; there has been a significant reduction in the prevalence of infection with Helicobacter

pylori as well as in the occurrence of peptic ulcer and gastric cancer in the Czech population. The article presents an overview of therapeutic

and preventive approaches in functional dyspepsia, peptic ulcer, gastroesophageal reflux disease, and nonsteroidal anti-inflammatory drug

gastropathy, with an emphasis on the use of the most effective antisecretory therapy, i.e. the treatment with proton pump inhibitors.

proton pump inhibitors.

Keywords: general practitioner, dyspepsia, peptic ulcer, gastroesophageal reflux disease, nonsteroidal anti-inflammatory drug gastropathy,