Med. praxi. 2013;10(2):68-71

Thyroid-associated orbitopathy from the perspective of ophthalmologist

MUDr.Marta Karhanová, FEBO, MUDr.Jana Kalitová
Oční klinika LF UP a FN Olomouc

Thyroid-associated orbitopathy is a chronic autoimmune disease with a proven connection to thyroid autoimmunity. Most often, patients

with Graves-Basedow disease are affected, however, it may also occur in those with autoimmune thyroiditis. This condition affects all the

structures of the orbit – extraocular muscles, orbital fat and connective tissue, orbital septum and tear gland. Various ocular symptoms

can also be the first sign of thyroid disease. In these cases, a good knowledge of ocular signs and symptoms of thyroid-associated orbitopathy

is necessary to establish the correct diagnosis. Only timely and appropriate treatment can prevent the serious consequences

of this disease.

Keywords: thyroid-associated orbitopathy, thyroid gland, exophthalmos, diplopia

Published: February 15, 2013  Show citation

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Karhanová M, FEBO, Kalitová J. Thyroid-associated orbitopathy from the perspective of ophthalmologist. Med. praxi. 2013;10(2):68-71.
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References

  1. Prabhakar BS, Bahn RS, Smith TJ. Current perspective on the pathogenesis of Graves' disease and ophthalmopathy. Endocr Rev 2003; 24: 802-835. Go to original source... Go to PubMed...
  2. Wiersinga WM, Kahaly GJ. Graves´ orbitopathy A multidisciplinary approach - Questions and answers. 2. vyd. Karger, 2010. Go to original source...
  3. Wiersinga WM, Bartalena L. Epidemiology and prevention of Graves´ ophthalmopathy. Thyroid 2002; 12: 855-860. Go to original source... Go to PubMed...
  4. McKeag D, Lane CM, Lazarus JH, et al. Clinical features of dysthyroid optic neuropathy: a European group on Graves' orbitopathy (EUGOGO) survey. Br J Ophthalmol 2007; 91: 455-458. Go to original source... Go to PubMed...
  5. Wiersinga WM, Prummel MF. Therapeutic controversies. Retrobulbar radiation in Graves´ ophthalmopathy. J Clin Endocrinol Metab 1995; 80(2): 345-347. Go to original source... Go to PubMed...
  6. Mouritz MP, Koornneef L, Wiersinga WM, et al. Clinical criteria for the assessment of disease activity in Graves´ ophthalmopathy: a novel approach. Br J Ophthalmol 1989; 73: 639-644. Go to original source... Go to PubMed...
  7. Eckstein A, Quadbeck B, Mueller G, et al. Impact of smoking on the response to treatment of thyroid associated ophthalmopathy. Br J Ophthalmol 2003; 87: 773-776. Go to original source... Go to PubMed...




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