Med. praxi. 2014;11(6):282-283
Fixed combination of perindopril and indapamide in patients with renal insufficiency
- II. interní klinika, Lékařská fakulta v Plzni, Univerzita Karlova v Praze, Plzeň
- Biomedicínské centrum, Lékařská fakulta v Plzni, Univerzita Karlova v Praze, Plzeň
Renal insufficiency is a relatively frequent complication or comorbidity in patients with arterial hypertension, particularly in those of
older age groups. To achieve target blood pressure levels is of particular importance in these patients. The treatment should be based
on a renin-angiotensin system blocker usually in combination with another antihypertensive drug. The article presents a case report of
a female patient in whom the use of a fixed combination of perindopril and indapamide resulted in hypertension control, was tolerated
very well, and did not result in impaired renal functions.
Keywords: perindopril, indapamide, fixed combination, renal insufficiency, arterial hypertension
Published: December 1, 2014 Show citation
References
- Cífková R, Bruthans J, Adámková V, Jozífová M, Galovcová M, Wohlfahrt P, et al. Prevalence základních kardiovaskulárních rizikových faktorů v české populaci v letech 2006-2009. Studie Czech post-MONICA. Cor et Vasa 2011; 53: 220-229.
Go to original source... - 2013 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC): ESH/ESC Task Force for the Management of Arterial Hypertension. J Hypertens 2013; 31(10): 1925-1938.
- Patel A, MacMahon S, Chalmers J, Neal B, Woodward M, Billot L, et al. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet 2007; 370(9590): 829-840. Go to original source...
Go to PubMed... - Beckett NS, Peters R, Fletcher AE, Staessen JA, Liu L, Dumitrascu D, et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med 2008; 358(18): 1887-1898. Go to original source... Go to PubMed...
- Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001; 358(9287): 1033-1041.
- Dahlof B, Gosse P, Gueret P, Dubourg O, de SG, Schmieder R, et al. Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study. J Hypertens 2005; 23(11): 2063-2070. Go to original source... Go to PubMed...
- Mogensen CE, Viberti G, Halimi S, Ritz E, Ruilope L, Jermendy G, et al. Effect of low-dose perindopril/indapamide on albuminuria in diabetes: preterax in albuminuria regression: PREMIER. Hypertension 2003; 41(5): 1063-1071. Go to original source... Go to PubMed...
- Mourad JJ, Hanon O, Deverre JR, Camici PG, Sellier P, Duboc D, et al. Improvement of impaired coronary vasodilator reserve in hypertensive patients by low-dose ACE inhibitor/diuretic therapy: a pilot PET study. J Renin Angiotensin Aldosterone Syst 2003; 4(2): 94-95. Go to original source... Go to PubMed...
- Asmar RG, London GM, O'Rourke ME, Mallion JM, Romero R, Rahn KH, et al. Amelioration of arterial properties with a perindopril-indapamide very-low-dose combination. J Hypertens Suppl 2001; 19(4): S15-S20.
- Heerspink HJ, Ninomiya T, Perkovic V, Woodward M, Zoungas S, Cass A, et al. Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease. Eur Heart J 2010; 31(23): 2888-2896. Go to original source... Go to PubMed...
- de Galan BE, Perkovic V, Ninomiya T, Pillai A, Patel A, Cass A, et al. Lowering blood pressure reduces renal events in type 2 diabetes. J Am Soc Nephrol 2009; 20(4): 883-892. Go to original source... Go to PubMed...
- Bangalore S, Kamalakkannan G, Parkar S, Messerli FH. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med 2007; 120(8): 713-719. Go to original source... Go to PubMed...
- Mancia G, Parodi A, Merlino L, Corrao G. Heterogeneity in antihypertensive treatment discontinuation between drugs belonging to the same class. J Hypertens 2011; 29(5): 1012-1018. Go to original source... Go to PubMed...
- Kuo SW, Pei D, Hung YJ, Hsieh AT, Wu LY, Hsieh CH, et al. Effect of indapamide SR in the treatment of hypertensive patients with type 2 diabetes. Am J Hypertens 2003; 16(8): 623-628. Go to original source... Go to PubMed...
- Ames RP. A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides. Am J Cardiol 1996; 77(6): 12b-6b. Go to original source... Go to PubMed...
- Agarwal R. Hypertension, hypokalemia, and thiazide-induced diabetes: a 3-way connection. Hypertension 2008; 52(6): 1012-1013. Go to original source... Go to PubMed...