Med. praxi. 2015;12(2):68-71

Non-healing wounds in diabetics

MUDr.Jan Stryja, Ph.D.
Komplexní kardiovaskulární centrum, Nemocnice Podlesí a.s., Třinec

Diabetes mellitus is a grave illness with rising up incidence in the Czech population. Diabetic foot ulcers are serious late complication of

diabetes. Many pathophysiological factors participate on the diabetic ulcer healing failure: diabetic polyneuropathy, macroangiopathy

and microangiopathy, acquired immunological disorders and tissue reparation failures in diabetics, present co-morbidities or drug adverse

reactions. The most common external causes of diabetic ulcers are: calluses, burns, skin splits, alien bodies penetrating the skin,

small injuries, mould infections, ingrowth nails and dactylitis. The treatment and pathophysiology of diabetic foot ulcers are complex.

Keywords: diabetic foot syndrome, ulcer, healing

Published: April 24, 2015  Show citation

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Stryja J. Non-healing wounds in diabetics. Med. praxi. 2015;12(2):68-71.
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    References

    1. Činnost oboru diabetologie, péče o diabetiky v roce 2012. Aktuální informace č. 24 Ústavu zdravotnických informací a statistiky České republiky. Praha 9. 7. 2013. Dostupný z: http://www.uzis.cz/category/tematicke-rady/zdravotnicka-statistika/diabetologie-pece-diabetiky.
    2. International Working Group on the Diabetic Foot. International Consensus on the Diabetic Foot & Practical Guidelines on the Management and Prevention of the Diabetic Foot 2011, The Nedherlands 2011. [Internet]. (C)2011 [cited 2013 May 21]. Dostupné z: http://www.iwgdf.org/index.php?option=com_content&task=view&id=16&Itemid=26
    3. Wagner FW. The dysvascular foot: A system for diagnosis and treatment. Foot Ankle. 1981; 2: 64-122. Go to original source... Go to PubMed...
    4. Lavery LA, Amstrong DG, Harkless LB. Classification of diabetic foot wounds. J Foot Ankle Surg. 1996 Nov-Dec; 35(6): 528-531. Go to original source... Go to PubMed...
    5. Škrha J. Diabetologie. 1. vyd. Praha: Galén; 2009. str. 64, 417 s.
    6. Škrha J. Oxidační stres a jeho vztah ke komplikacím diabetu. Interní Med. 2010; 12(9): 414-418.
    7. Broulíková A. Diabetes mellitus a cévní onemocnění. Interní med. 2011; 13(5): 199-201.
    8. Vinik Al, Erbas T, Park TS, Nolan R, Pittenger GL. Platelet dysfunction in type II diabetes. Diabetes Care. 2001 Aug; 24(8): 1476-1485. Go to original source... Go to PubMed...
    9. Jirkovská A et al. Syndrom diabetické nohy. 1.vyd. Praha: Maxdorf; 2006. str. 32, 400 p.
    10. Kannel WB, McGee DL. Diabetes and cardiovascular disease. The Framingham study. JAMA.1979 May 11; 241(19): 2035-2038. Go to original source... Go to PubMed...
    11. Selvin E, Marinopoulos S, Berkenblit G, Rami T, Brancati FL, Powe NR, Golden SH. Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus. Ann Intern Med. 2004 Sep; 141(6): 421-31. Go to original source... Go to PubMed...
    12. Staffa R. Záchrana kriticky ischemické končetiny - pedální bypass. Vyd. 1. Praha: Grada Publishing, a.s.; 2005. str. 32, 112 p.
    13. Lacigová S, Jirkovská A, Rušavý Z. Standardy diagnostiky a léčby diabetické neuropatie. DMEV. 2012; 15(1): 35-40.) [Internet]. (C)2012 [cited 2013 May 22]. Dostupné z: http://www.tigis.cz/images/stories/DMEV/2012/01/07_standard_neuropatie_dmev_1-12.pdf.
    14. Tesfaye S, Boulton AJ, Dyck PJ, Freeman R, Horowitz M, Kempler P, Lauria G, Malik RA, Spallone V, Vinik A, Bernardi L, Valensi P. Toronto Diabetic Neuropathy Expert Group. Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes Care. http://www.ncbi.nlm.nih.gov/pubmed/208767092010 Oct; 33(10): 2285-2293. Go to original source... Go to PubMed...
    15. Jirkovská A, Bém R. Praktická podiatrie. Základy péče o pacienty se syndromem diabetické nohy. 1. vyd. Praha: Maxdorf; 2011. str. 35, 139p.
    16. Fejfarová V, Jirkovská A. Syndrom diabetické nohy. Diabetologie. Postgraduální medicína. 2011; 13(4): 414-423.
    17. Marhoffer W, Stein M, Maeser E, Federlin K. Impairment of polymorphonuclear leukocyte function and metabolic control of diabetes. Diabetes Care. 1992 Feb; 15(2): 256-260. Go to original source... Go to PubMed...
    18. Eneroth M, Larsson J, Apelqvist J. Deep foot infections in patients with diabetes and foot ulcer: an entity with different characteristics, treatments, and prognosis. J Diabetes Complications. 1999 Sep-Dec; 13(5-6): 254-263. Go to original source... Go to PubMed...
    19. Jirkovská A, Lacigová S, Rušavý Z, Bém R. Doporučený postup péče o nemocné se syndromem diabetické nohy. Diabetologie metabolismus endokrinologie výživa. 2012; 15 (1): 42. [Internet]. (C)2012 [cited 2013 May 21]. Dostupné z: http://www.tigis.cz/images/stories/DMEV/2012/01/08_standard_diab_noha_dmev_1-12.pdf.
    20. Falanga V. Wound healing and its impairment in the diabetic foot. Lancet. 2005 Nov 12; 366(9498): 1736-1743. Go to original source... Go to PubMed...

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