Med. praxi. 2015;12(3):143-145
Austrian syndrome - a rare type of invasive pneumococcal disease
- 1 Klinika infekčního lékařství, Fakultní nemocnice Ostrava
- 2 Ústav patologie, Fakultní nemocnice Ostrava
Pneumococcal endocarditis associated with pneumonia and purulent meningitis is known as Austrian Austrian syndrome. We present
a case report of 67-year old patient with coma and left-sided hemiparesis due to purulent meningitis. He subsequently developed
pneumonia and sepsis with cerebral absceses. The patient died on the 20th day of illness. Post-mortem examination showed mitral
endocarditis. Trans-thoracic echocardiographic examination was negative. Streptococcus pneumoniae serotype 10A was detected from
the cerebrospinal fluid. The patient was not vaccinated. Serotype 10A is contained in 23-valent polysaccharide vaccine. Vaccination is
the only effective prevention of the disease. It is desirable to increase the vaccination coverage in adults.
Keywords: Austrian syndrome, meningitis, endokarditis, pneumonia, Streptococcus pneumoniae, vaccination
Published: June 24, 2015 Show citation
References
- Chlíbek R, Smetana J, Boštíková V, et al. Očkování proti pneumokokovým onemocněním v dospělosti. Vakcinologie 2014; 8(3): 118-124.
- Galský J. Pneumokokové infekce. In: Beneš J. Infekční lékařství. 1. vyd. Praha: Galén; 2009: 201-203.
- Smetana J, Kosina P, Boštíková V, et al. Austrianův syndrom: pneumokoková meningitida, pneumonie a endokarditida - kazuistika. Cesk Slov Neurol N 2012; 75/108(4): 494-497.
- Kanakadandi V, Annapureddy N, Agarwal SK, et al. The Austrian syndrome: a case report and review of the literature. Infection 2013; 41(3): 695-700.
Go to original source... 
Go to PubMed... - Gonzalez-Juanatey C, Testa A, Mayo J, et al. Austrian syndrome: report of two new cases and literature review. Int J Cardiol 2006; 108(2): 273-275. Go to original source... Go to PubMed...
- Aronin SI, Mukherjee SK, West JC, et al. Review of pneumococcal endocarditis in adults in the penicillin era. Clin Infect Dis 1998; 26(1): 165-171. Go to original source... Go to PubMed...
- Mankongpaisarnrung C, Soontrapa S, Nantsupawat T, et al. Renal infarction as a presentation of Austrian syndrome: thromboembolic phenomenon of pneumococcal endocarditis. Am J Med Sci 2012; 344(3): 251-254. Go to original source... Go to PubMed...
- Belvisi V, Del Borgo C, Morelli F, et al. Late onset invasive pneumococcal disease in a liver transplanted patient: beyond the Austrian syndrome. Transpl Infect Dis 2013; 15(3): 111-114. Go to original source... Go to PubMed...
- Du Cheyron D, Lesage A, Le Page O, et al. Corticosteroids as adjunctive treatment in Austrian's syndrome (pneumococcal endocarditis, meningitis, and pneumonia): report of two cases and review of the literature. J Clin Pathol 2003; 56(11): 879-881. Go to original source... Go to PubMed...
- Vindas-Cordero JP, Sands M, Sanchez W. Austrian's triad complicated by suppurative pericarditis and cardiac tamponade: a case report and review of the literature. Int J Infect Dis 2009; 13(1): e23-25. Go to original source... Go to PubMed...
- http://www.infekce.cz/Standardy/IEDP.pdf.
- Kozáková J, Šebestová H, Křížová P. Invazivní pneumokokové onemocnění v České republice v roce 2013. Zprávy CEM (SZÚ, Praha) 2014; 23(3): 89-97.
- http://www.vakcinace.eu/data/files/ockov_kal_2015.pdf.