Med. praxi. 2024;21(4):247-253 | DOI: 10.36290/med.2024.030

Effect of paracetamol on blood pressure and comparison with NSAIDs

MUDr. Michal Prokeš, PharmDr. Josef Suchopár
DrugAgency, a. s., Praha

It is well known that suboptimal treatment of hypertension increases patient morbidity and mortality and that NSAIDs belong to the drugs that can raise blood pressure. Until recently, paracetamol was considered an analgesic that does not have such effects. However, some new information raises concerns about the safety of at least some patients with arterial hypertension when taking paracetamol. This review article presents information on the possible effect of paracetamol and NSAIDs on the blood pressure of hypertensive and non-hypertensive patients. From the available data, it appears that the negative impact of NSAIDs is more intense than the effect of paracetamol.

Keywords: paracetamol, NSAID, hypertension, antihypertensives effectiveness.

Received: July 16, 2024; Revised: August 21, 2024; Accepted: August 30, 2024; Published: October 2, 2024  Show citation

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Prokeš M, Suchopár J. Effect of paracetamol on blood pressure and comparison with NSAIDs. Med. praxi. 2024;21(4):247-253. doi: 10.36290/med.2024.030.
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