Med. praxi. 2015;12(2)
Med. praxi. 2015;12(2):59-60
Prevalence of arterial hypertension in the Czech Republic is around 40%. Blood pressure control is unsuccessfull despite of a big potencial of pharmacotherapy. Appropriate blood pressure measurement and ambulatory and home blood pressure monitoring have to be considered. Secondary hypertension must be excluded when suspected. There is a lack in compliance with lifestyle recommendations and pharmacotherapy. Pharmacotherapy dosing must be sufficient, including diuretics in combination therapy. Fixed combinations and valuable communication with patients should be effected.
Med. praxi. 2015;12(2):62-63
An interdisciplinary approach in vaccination consists in the development of guidelines and consensus statements by various medical professional societies for vaccinating selected risk groups of patients. This approach should reduce the inconsistency in approaching vaccination and result in specifying a uniform vaccination scheme acceptable across various specialities. This would lead to a wider use of vaccination, extended spectrum of vaccinating medical specialities, and a better perception of the significance of vaccination by both physicians and, subsequently, patients. Examples of implementing the recommendation to vaccinate in the guidelines...
Med. praxi. 2015;12(2):64-66
Rosacea is a chronic inflammatory skin disorder characterized by four distinct clinical stages predominantly affecting the central area of the face.Rosacea affects mostly adults over the age of 30, with a higher incidence in women. We categorized pathological mechanisms of rosacea in innate immunity, vascular changes, reactive oxygen species, ultra violet radiation and microbes. The disease has a variety of clinical manifestations that include flushing, persistent erythema, papules and telangiectasia. Treating rosacea varies depending on severity and subtypes. Demodex folliculorum end Demodex brevis are obligatory parasites in hair follicles...
Med. praxi. 2015;12(2):68-71
Diabetes mellitus is a grave illness with rising up incidence in the Czech population. Diabetic foot ulcers are serious late complication of diabetes. Many pathophysiological factors participate on the diabetic ulcer healing failure: diabetic polyneuropathy, macroangiopathy and microangiopathy, acquired immunological disorders and tissue reparation failures in diabetics, present co-morbidities or drug adverse reactions. The most common external causes of diabetic ulcers are: calluses, burns, skin splits, alien bodies penetrating the skin, small injuries, mould infections, ingrowth nails and dactylitis. The treatment and pathophysiology of diabetic...
Med. praxi. 2015;12(2):72-76
Nimesulide is a nonsteroidal anti-inflammatory drug preferentially blocking cyclooxygenase 2, and therefore has a lower gastropatic manifestations. The analgesic and anti-inflammatory activity is not only central but also peripheral. According to the analgesic ladder is administered as monotherapy or in combination for the treatment of acute vertebral pain, post-traumatic and postoperative conditions or dysmenorrhea. For menstrual migraine is used seven day prophylactic cure. Nimesulid is effective in the treatment of acute migraine attack and tension-type headache. It is an alternative medication by intolerance or contraindications to other...
Med. praxi. 2015;12(2):77-82
Multiple sclerosis is an immunopathological disease characterized by an inflammation of the structures of the central nervous system and neurodegenerative changes in the brain. The initial neurological complaints, due to which the risk of developing clinically definite multiple sclerosis is suspected, are referred to as clinically isolated syndrome. The diagnosis of the disease is based on the clinical evaluation of the patient's problems and neurological examination. Magnetic resonance imaging of the brain and spinal cord supported by cerebrospinal fluid examination plays an indispensable role. The results of clinical studies and research...
Med. praxi. 2015;12(2):83-86
Erectile dysfunction is no longer considered to only be a condition impairing the patient's mental well-being, but also a significant risk factor associated with many serious diseases, particularly of vascular aetiology. Organic causes, whether vasculogenic, endocrine, neurogenic, etc., are the most common reason for developing this disease, with purely psychogenic factors occurring less frequently. However, a psychic component is almost invariably present to some degree, usually as an additional psychogenic overlay. The role of the physician is to detect erectile dysfunction patients early, try to win their cooperation, and begin to solve...
Med. praxi. 2015;12(2):92-94
Cerebral venous thrombosis (CVT) is a disease of the cerebral veins and sinuses, with a number of acquired and congenital factors being involved in its development. It is a serious condition manifested by a variety of clinical signs and a variable course. CVT occurs in both sexes and all age groups, with newborns and women of childbearing age being most commonly affected. The occurrence of CVT in young women is particularly increased in the postpartum period, when taking hormonal contraception, and in thrombophilia. The thrombophilic state is a haemostasis disorder characterized by an increased tendency to blood coagulation and thrombus formation....