Budoucnost asistivních technologií v medicíně

doc. Ing. Lenka Lhotská, CSc.

Med. praxi. 2018;15(5):239  

Fabry disease

MUDr. Gabriela Dostálová, MUDr. Petra Reková, MUDr. Klára Sedláková, Ph.D., MUDr. Ondřej Kodet, MUDr. Alena Slováková, MUDr. Kristýna Bayerová, MUDr. Lenka Roblová, MUDr. Lubor Goláň, prof. MUDr. Aleš Linhart, DrSc.

Med. praxi. 2018;15(5):242-244  

Fabry disease is an X-linked lysosomal storage disease. Enzyme replacement therapy (ERT) is available in our country since 2004.The sooner diagnosis is made, the better ERT stabilizes the progression of Fabry disease. The timing of ERT is important in orderto prevent irreversible organ damage.

Symptomatic treatment of influenza and its limitations caused by age, flu-related risks in geriatric patients

MUDr. Ondřej Výška, MUDr. Matúš Mihalčin, prof. MUDr. Hana Matějovská Kubešová, CSc.

Med. praxi. 2018;15(5):246-250 | DOI: 10.36290/med.2018.046  

Influenza is a highly contagious infectious disease with a seasonal prevalence. Senescence is accompanied by involutional changesin the organism, which can result in a changed symptomatology of infectious diseases. These changes in the body's response needto be taken into account both during diagnosis and therapy to avoid delayed or misdiagnosis, which could have fatal consequences.

Over-the-counter medications in treatment of the benign prostatic hyperplasia

Mgr. Ondřej Šimandl

Med. praxi. 2018;15(5):251-257  

Benign prostatic hyperplasia belongs among benign, but if not treated, progressive disease significantly affecting the quality oflife of men after the 40th year of life. With age the incidence of this disease is increasing.Article aims to inform the reader with currently available products intended for self-medication of syndrome of the lower urinarytract, thus clinically expressed symptoms of benign prostatic hyperplasia. These are mainly phytopharmaceuticals containingmostly extract from the fruit of the weed dwarf palm Serenoa repens.In addition to the list of trade names of OTC preparations, their composition and recommended dosages, the article...

The posibilities of combination pharmacotherapy of arterial hypertension and dyslipidemia in cardiovascular risk reducing

MUDr. Barbora Nussbaumerová, Ph.D.

Med. praxi. 2018;15(5):258-260 | DOI: 10.36290/med.2018.066  

Hypertension and dyslipidaemia are the most important risk factors of atherosclerotic vascular diseases. Most of hypertensivepatients need combination treatment to reach target blood pressure values. The first line combination contains ACE inhibitors/AT1 blockres and calcium channel blockers or diuretics. About 70 % of hypertensive patients suffer from dyslipidaemia. Statintherapy must be taken in account, according to the total cardiovascular risk. Fixed combinations improve compliance and efficacyof the treatment. Antihypertensive drugs, hypolipidemics and also the combination of both are available in fixed combinations.

Actualities in functional esophageal disorders

MUDr. Štefan Konečný, MUDr. Radek Kroupa, Ph.D., MUDr. Jiří Dolina, Ph.D.

Med. praxi. 2018;15(5):263-266 | DOI: 10.36290/med.2018.048  

Functional Gastrointestinal Disorders, better defined as Disorders of Gut-Brain Interaction are clinical futures without a structuralbasis. This review is focused on Functional Esophageal Disorders and their treatment based on latest guidelines and Rome IVClassification.

Incontinence – innovations and options for treatment in a general practitioner's office

MUDr. Miroslava Ryšánková

Med. praxi. 2018;15(5):276-280 | DOI: 10.36290/med.2018.050  

Urine incontinence is any (even small) involuntary leakage of urine. It affects all ages, including children. However, as the urinarytract develops for up to 12 years, the leakage can be tolerated as physiological until this age. Then it becomes burdensome psychologicallyand socially as well as economically. Accurate statistics on occurrence are not entirely objective. Many patients donot talk about the problem. For example: patients in social facilities, persons over the age of 60th or many younger patients whoare ashamed to talk about their problem, despite the raising the awareness of this issue.

Preparations intended for the care of the skin suffering from atopic dermatitis

Mgr. Jana Martinásková

Med. praxi. 2018;15(5):281-286  

The article discusses the current knowledge regarding the predisposition to develop atopic dermatitis. Summarizes generallyknown recommendations for skin care suffering from AD. The surveillance tables provide examples and composition of OTCdermocosmetics and medicines that are available in pharmacies. The examples given dermocosmetics brands were selectedbased on their market position, long-term experience of the companies in the development of the products, collaboration withdermatologists and based on the positive response to the patient’s side.

Drug-drug interactions of warfarin and new direct oral anticoagulans

MUDr. Michal Prokeš, PharmDr. Josef Suchopár

Med. praxi. 2018;15(5):267-275 | DOI: 10.36290/med.2018.049  

Anticoagulation therapy with warfarin and direct oral anticoagulants annually saves lives of many patients. These patients oftentake medicines that change the effect of anticoagulants. This article attempts to present in a synopical way information about suchinteractions that physicians prescribe. Although warfarin has more interactions than DOAC, some DOAC interactions are equallydangerous and, unlike warfarin, the effect of DOAC cannot be easily monitored. This may be a problem because there are patients inwhom the drug interaction is more intense than in average patients, for example when dabigatran is combined with clarithromycin.

Care of ostomy patients

Radomíra Fierlová

Med. praxi. 2018;15(5):291-294 | DOI: 10.36290/med.2018.069  

For a patient, an ostomy means not only a change in their condition, but also a change in their physical appearance, function,and psyche. The treatment success in a patient with an ostomy does not depend on a single person, but on the collaborationof a whole team of doctors and nurses. An ostomy nurse’s goal is to facilitate the return to normal life by providing appropriateeducation, choosing the right ostomy supplies, and offering emotional support in close cooperation with the family.

Terapie hyperlipidemie

MUDr. Pavel Rutar

Med. praxi. 2018;15(5):287-290