Nepříjemná letní setkání

doc. MUDr. Ladislav Machala, Ph.D.

Med. praxi. 2011;8(7):307  

Long term therapy of osteoporosis

MUDr.Martina Skácelová, prof.MUDr.Pavel Horák, CSc., MUDr.Martin Žurek, Ph.D.

Med. praxi. 2011;8(7):310-316  

Osteoporosis is the most common metabolic bone disease which leads to an increased risk of fractures. Products used in therapy reduce bone resorption or stimulate bone formation. There are many unanswered questions in the treatment of osteoporosis regarding the efficacy and safety of long-term therapy, as well as an assessment of its effects or risks associated with the discontinuation of treatment. Bisphosphonates are potent inhibitors of the bone resorption, their prolonged use increases bone mineral density in the lumbar spine and hip and reduces the risk of osteoporotic fractures. Discontinuation of bisphosphonates increases the bone resorption...

Hypolipidemic therapy in the hands of a general practitioner

MUDr.Lukáš Zlatohlávek, Ph.D., MUDr.Michal Vrablík, Ph.D., prof.MUDr.Richard Češka, CSc.

Med. praxi. 2011;8(7):316-320  

Cardiovascular disease is the most common cause of mortality and morbidity in the Czech Republic. Dyslipidemia is one of the causal parameters by affecting which the cardiovascular risk can be reduced substantially. Selecting a proper hypolipidemic drug is often crucial in selectively affecting the lipid spectrum. If possible, it is necessary to adhere to the recommended target levels as closely as possible. On the other hand, however, it is necessary to realize that the treatment often has to be individualized. In hypolipidemic therapy, monitoring the patient’s lipid panel as well as the “safety” indicators is of importance....

Nonalcoholic steatohepatitis, possibilities of diagnosis and treatment of keratin fragments

prof.MUDr.Jan Lata, CSc., MUDr.Veronika Příbramská

Med. praxi. 2011;8(7):321-324  

Fatty liver disease that develops in the absence of alcohol abuse is increasingly recognised as a major health burden. Non-alcoholic steatohepatitis is disease that histologically mimics alcoholic hepatitis. The diagnostic criteria continue to evolve and rely on the histologic findings of steatosis, hepatocellular injury including lobular inflammation and the pattern of fibrosis in patients with minimal intake of ethanol (< 20 g ethanol/day). Recently has been studied extensively as it is relatively frequent, and might lead to the development of liver cirrhosis and hepatocellular carcinoma. The pathophysiologic basis is thought to be insulin...

Climacteric medicine and general practitioner

prof.MUDr.Josef Donát, DrSc.

Med. praxi. 2011;8(7):326-329  

Climacteric medicine is a multidisciplinary branch of medicine, contains prevention and treatment of the wide scale of health complaints by women and men, in connection to the aging. Most of these complaints in women develops on the basis of estrogen deficiency and primarily needs estrogen therapy. In early postmenopause in age 50-59 years estrogens are a prevention of the coronary heart disease and postmenopausal osteoporosis. General practitioner should play the main role in prevention and treatment of health problems of the climacteric medicine, just besides in addition to gynecologist.

Treatment of depression in old age

prof.MUDr.Eva Češková, CSc.

Med. praxi. 2011;8(7):330-333  

Depressive disorder is the most common mental disorder (after memory impairment) in old people. In the development of late-life depression hereditary factors may play minor part, biological factors and psychosocial stress being more important. Late-life depression has partially a different clinical picture including a higher risk of suicidal behaviour. In efficacy of antidepressants no significant differences were found between younger and older people with depression. Therefore safety and tolerability of individual antidepressants represent the most important criterion for treatment choice in common clinical practice. Nowadays, an individualized...

Celiac disease - extragastrointestinal manifestations in adults

MUDr.Marta Pískovská

Med. praxi. 2011;8(7):333-336  

The case report should aid general practitioners and internists in diagnosing celiac disease in adults in patients with an oligosymptomatic form with disease manifestations with no gastrointestinal symptoms. In the case of symptoms such as sideropenic anemia, chronic fatigue, age-inappropriate osteoporosis, difficulties becoming pregnant and repeated abortions of unknown etiology, burning of the tongue and enamel disorders, skin exanthem, depression and tendency to anxiety, the differential diagnosis should include celiac disease. A higher risk is found in patients with another previously manifested autoimmune disease frequently linked to celiac...

Enteral and parenteral nutrition in patients with inflammatory bowel disease

MUDr.Mgr.Drahomíra Vrzalová, MUDr.Michal Konečný, Ph.D., prof.MUDr.Jiří Ehrmann, CSc.

Med. praxi. 2011;8(7):337-338  

Nutritional disorders are a concomitant phenomenon in patients with inflammatory bowel disease. Dietary measures and administration of various forms of enteral and parenteral nutrition are an integral part of treatment for Crohn‘s disease and ulcerative colitis in both the hospital and home setting.

Chronic kidney failure and its treatment from the perspective of a general nurse

Bc.Jindra Kracíková

Med. praxi. 2011;8(7):339-341  

Chronic kidney disease is common and has serious consequences for the patient but, in economic terms, for the whole society. Chronic kidney disease is often asymptomatic and is recognized only after reaching the end stage, i. e. chronic kidney failure. Chronic kidney failure (CKF) is a condition when renal function is decreased to such a degree that the kidneys are unable to maintain the normal composition of the internal environment even under basal conditions, with special dietary and medical measures and in a balanced metabolic situation of the organism, and it is necessary to initiate treatment with one of the methods to replace renal function....

Autodidaktický test 7/2011

Med. praxi. 2011;8(7):342-343