Rakovina – nemoc celé rodiny

Mgr. Radka Alexandrová

Med. praxi. 2018;15(1):3  

Possible kidney injury in association with the use of common anti-infective agents

MUDr. Jan Vachek, PhDr. MUDr. Oskar Zakiyanov, Ph.D., prof. MUDr. Vladimír Tesař, DrSc.

Med. praxi. 2018;15(1):6-8 | DOI: 10.36290/med.2018.002  

Kidney injury is among frequent complications of pharmacotherapy in both outpatients and inpatients. Although it most often isa condition that is usually asymptomatic and resolves spontaneously without developing serious sequelae, in some cases it maylead to temporary or permanent loss of renal function and the need for replacement of renal function. In hospitalized patients,in particular, acute kidney injury is associated with high morbidity and mortality. This paper presents a review of potential nephrotoxicityof common anti-infective agents with respect to the needs of a specialist in outpatient practice.

Uncomplicated lower urinary tract infections in women – options of treatment and prevention in the general practitioner’s surgery

MUDr. Jiří Kladenský

Med. praxi. 2018;15(1):9-14 | DOI: 10.36290/med.2018.056  

Urinary tract infections (UTIs) are among very frequent medical conditions for which women visit their general practitioner. Acuteuncomplicated cystitis the diagnosis of which is usually straightforward is the most common manifestation of UTIs in women. Whenchoosing an appropriate antimicrobial agent, it is advisable to take into consideration its pharmacokinetics, the assumed spectrumof efficacy, and the effect on the vaginal flora. Short-term treatment with a duration of three to five days is preferred. In women withrecurrent cystitides, following the commencement of appropriate therapy and retreatment of infection, it is necessary to perform acomprehensive...

Lower respiratory tract infections and their complications

MUDr. Václava Bártů, Ph.D.

Med. praxi. 2018;15(1):15-19 | DOI: 10.36290/med.2018.057  

Respiratory tract infections are among the most common reasons for seeking care from general practitioners and paediatricians.They are usually of viral aetiology, but secondary bacterial infections are also frequent. In the case of recurrent infections, it is vitalto determine the cause that leads to repeated episodes of inflammation. Associated conditions, including diabetes mellitus, ischaemicheart disease, chronic obstructive pulmonary disease, liver disease, kidney disease, tumour disease, and immunosuppressivetreatment for various other conditions, represent a major risk factor that may seriously complicate respiratory tract disease to thepoint...

Rhinitis and inflammation of the nasal sinuses

Mgr. Ondřej Šimandl

Med. praxi. 2018;15(1):20-25  

Rhinitis and inflammation of the nasal sinuses, which significantly deteriorate the quality of life of the patient, are among themost frequent reasons for visiting a pharmacy. However, in the event of persistent problems or complications, the patient usuallyseeks medical advice. This article introduces the reader to the possibilities of self-treatment of rhinitis and rhinosinusitis with theuse of over-the-counter products and appropriate regimens associated with the treatment and prevention of this disease. In theintroduction, the paper addresses the causes of inflammatory diseases of the nasal cavities development and symptomatology– their knowledge...

Optimal treatment of venous thromboembolism

doc. MUDr. Radovan Malý, Ph.D.

Med. praxi. 2018;15(1):26-29 | DOI: 10.36290/med.2018.004  

Venous thromboembolism involving deep vein thrombosis as well as pulmonary embolism represents a frequent and costlydisease that is associated with high morbidity and mortality rates. The main goal of treatment is to prevent pulmonary embolismand death related to venous thrombosis and pulmonary embolism as well as to prevent chronic venous insufficiency and chronicthromboembolic pulmonary hypertension. In addition to treatment with low-molecular-weight heparin and warfarin, there hasbeen a trend in the last five years to increasingly use direct oral anticoagulants in treatment; these include the so-called xabans(rivaroxaban, apixaban, edoxaban), direct...

The most common mistakes in the treatment of depression in primary care

MUDr. Sylva Racková, Ph.D.

Med. praxi. 2018;15(1):33-37 | DOI: 10.36290/med.2018.006  

Depression belongs among very frequent and well treated disorders. It is important to follow the guidelines in the treatmentdepression. We are concerned with farmacotheraphy of depression, what is important and witch mistakes are more frequent inthe pharmacotheraphy.

L-tryptofan – a nutraceutical with impact on mental health

MUDr. Dana Kamarádová, Ph.D., prof. MUDr. Vilím Šimánek, DrSc.

Med. praxi. 2018;15(1):38-42 | DOI: 10.36290/med.2018.007  

L-tryptophan is an essential amino acid of the human diet. Apart from its incorporation into body proteins, L-tryptophan is theprecursor of serotonin and other neurotransmitters in the brain and gastro intestinal tract. This brief overview covers the role ofL-tryptophan in brain serotonin synthesis as an important factor in mood, cognition and social behaviour.

Late sequelae of head injury from the perspective of an endocrinologist

MUDr. Jan Schovánek, Ph.D., MUDr. Ľubica Cibičková, Ph.D., doc. MUDr. Zdeněk Fryšák, CSc.,, doc. MUDr. David Karásek, Ph.D.

Med. praxi. 2018;15(1):43-45 | DOI: 10.36290/med.2018.008  

Head injuries have been an increasing challenge for the whole society, representing the leading cause of death and permanent disabilityin young men. Traumatic head injuries most commonly occur as a result of traffic accidents, falls, violence, sports injuries, and last butnot least as part of war injuries. The mechanism of origin of an endocrine disorder at first glance appears obvious and unquestionable,but upon looking more closely, one finds that its exact pathophysiological mechanisms have not yet been established. These can becontributed to by autoimmune mechanisms and the extent of sequelae in a traumatic head injury can even be influenced by...

Occupational diseases – diagnostics and treatment

MUDr. Martin Novák

Med. praxi. 2018;15(1):53-56  

In the article we present the most important occupational diseases with brief features , diagnostics and principles of their treatment.The importace of correct process concerning therapeutic and preventive care is emphesized.

The care of the periwound area

Mgr. Romana Procházková, doc. PhDr. Andrea Pokorná, Ph.D.

Med. praxi. 2018;15(1):49-52  

Periwound tissue of the chronic/non-healing wound is fragile and requires proper treatment throughout the so-called phase healing.The main goal is to keep the wound environment and periwound skin calm, clean and hydrated, thus supporting the woundclosure process through epithelization. Care of the wound environment within wound management requires the attention ofcaregivers and early intervention in case of complications. There are many products on the market to clean and treat periwoundskin and appropriate products selection is important. We deal with the topic of periwound tissue and skin care in general andwe also present a case report.

Influenza – permanent threat for mankind

MUDr. Ján Dindoš

Med. praxi. 2018;15(1):29 | DOI: 10.36290/med.2018.005  

Influenza is very high infectious diesease, contagious with infected air, which in Europe and Czech Republic begins at the endof December, has culmination from January to March and finished on the beginning of May. Influenza had typical symptoms,from which are very important: very high fever, ague, headache and pains of joints and muscles. In prevention of disease is veryimportant fact of vacccination, which is in the Czech Republic underestimated until now.

Syndrom dráždivého tračníku

MUDr. Pavel Rutar

Med. praxi. 2018;15(1):30-32  

Fytofarmaka – možnosti a rizika

MUDr. Pavel Rutar

Med. praxi. 2018;15(1):46-48  

Onemocnění způsobená poruchami fosfokalciového metabolismu

MUDr. Pavel Rutar

Med. praxi. 2018;15(1):57-58