Sdělování špatné zprávy (1. část)

MUDr. Radkin Honzák, CSc.

Med. praxi. 2023;20(3):131  

Biologic treatment of migraine

MUDr. Petra Migaľová

Med. praxi. 2023;20(3):135-140 | DOI: 10.36290/med.2023.020  

Migraine is the third most common neurological disease. It is also one of the most disabling diseases in the world. About a billion people are suffering from migraine around the world. There are around one million patients with migraine in the Czech Republic. At least 50 000 women and men suffer from chronic migraine. Since 1993, we have had a specific acute antimigraine drug, triptans. Since 2020, targeted biological treatment has been available, which significantly reduces the number of migraine attacks and improves the patient's quality of life. Since 2022 another acute and prophylactic treatment, gepanty, is available.

Preventive care in the Czech Republic - what the general practitioner should know

doc. MUDr. Bohumil Seifert, Ph.D.

Med. praxi. 2023;20(3):141-146 | DOI: 10.36290/med.2023.021  

In few countries in the world do general practitioners have such a role in prevention as in the Czech Republic. They actively intervene in all areas of prevention. Together with their nurses in surgeries, they have the best opportunity for all health professionals to influence patients in the field of primary prevention. They play a crucial role in secondary prevention and in the screening programs that are part of it. Together with doctors of other specializations, it works in tertiary prevention. And they have a very specific mission in quaternary prevention. Czech general practitioners should excel in knowledge in the field of prevention and mediate...

The importance of adrenaline autoinjector

MUDr. Magdalena Herknerová, Ph.D.

Med. praxi. 2023;20(3):147-150 | DOI: 10.36290/med.2023.022  

Adrenaline delivery via adrenaline autoinjectors represents a rapid and life-saving first-line treatment of anaphylaxis. Adrenaline administration via autoinjector results in the more rapid achievement of peak systemic delivery of adrenaline. This paper brings data about adrenaline autoinjector prescription based on the optimal diagnostics (example of component resolved diagnostics in food-induced anaphylaxis) and the adequate usage of adrenaline autoinjector.

Pulmonary embolism, the current approach in diagnosis and treatment

MUDr. Adam Koudelka, prof. MUDr. Ondřej Ludka, Ph.D., MUDr. Michaela Habánová, MUDr. Petr Lokaj, Ph.D.

Med. praxi. 2023;20(3):151-156 | DOI: 10.36290/med.2023.023  

Pulmonary embolism is one of the three most common emergent cardiovascular events. Concerning the related symptoms, it is always considered an urgent state of dyspnoea and chest pain. Its incidence is still increasing with the improving availability of laboratory and imaging methods. On the other hand, per case mortality is decreasing. With the introduction of direct oral anticoagulants into daily practice and the new extension of recommendations also among oncology patients, its treatment is significantly simplified. This can be useful not only in hospital treatment but especially in properly selected patients treated exclusively on an outpatient...

Climacteric patient in office of general practitioner

doc. MUDr. Tomáš Fait, Ph.D.

Med. praxi. 2023;20(3):157-162 | DOI: 10.36290/med.2023.024  

Hormone replacement therapy (HRT) is the most effective treatment for acute climacteric syndrome and has been proven to prevent bone loss and fractures. In women within 10 years of the onset of menopause it is prevention of atherosclerosis and dementia. Later initiation of treatment is on opposite side connected with the worsening of these processes. We prefer the lowest doses of estrogen and natural type of gestagen for higher safety especially from the breast cacer risk point of view. For women which prefer nonhormonal therapy we have broad offer of alternative medicine. Some of them have scientific confirmation of safety and efficacy (DT56a soya...

A patient suffering from peripheral arterial disease in a general practitioner's office

MUDr. Matej Pekař, Ph.D., MBA, MUDr. Lubomír Blaha, MBA, MUDr. Martin Novák

Med. praxi. 2023;20(3):163-165 | DOI: 10.36290/med.2023.025  

Every patient suspected from peripheral arterial disease (PAD), a patient with claudication, resting ischemic pain of the lower limbs (LL) or with non-healing LL defects should undergo an angiological examination. It is important to keep in mind the existence of the diagnosis of PAD, which is quite widespread in the population. Correctly taken medical history, performed clinical examination and timely referral of the patient to a specialist can save the patient's limb and save it from amputation. This article aims to introduce the issue of PAD to first-line doctors.

Hypo/hypervitaminosis, part 2 - Fat­‑soluble vitamins

Mgr. Miroslava Kamenská

Med. praxi. 2023;20(3):180-184 | DOI: 10.36290/med.2023.028  

This article summarizes current information about the function, source, and bioavailability of fat-soluble vitamins A, D, E, and K. Furthermore, it shows dietary reference values stated by European Food Safety Authority for the adult population, lists hypovitaminosis high-risk groups and states potential complications that could arise from ingesting these compounds.

Herbal preparations in trealing benign prostatic hyperplasia

PharmDr. Alice Sychrová, Ph.D.

Med. praxi. 2023;20(3):166-170  

Benign prostatic hyperplasia affects men from the age of 40 and its prevalence increases with age. Millions of men worldwide suffer from this disease, with many of them choosing an alternative treatment approach using phytotherapeutics, which are available in the form of registered preparations or food supplements. These preparations contain extracts that have been tested in clinical studies. Many of these studies have been critically evaluated by systematic reviews and meta-analyses. Recent data shows that saw palmetto (Serenoa repens) has a significant effect. Other drugs used in the treatment of BPH/LUTS include stinging nettle, lycopene,...

Treatment of chronic pain-up to date

MUDr. Pavlína Nosková, Ph.D.

Med. praxi. 2023;20(3):171-178 | DOI: 10.36290/med.2023.027  

Chronic pain is a serious health problem that puts a strain on the entire health system. Her treatment should be conducted rationally and on the basis of current scientific knowledge. The article summarizes the current view of this issue and points to new painkillers and recommendations.

Ambulantní monitorace krevního tlaku

MUDr. Jan Hůlka

Med. praxi. 2023;20(3):185-186 | DOI: 10.36290/med.2023.029  

Deprese u somaticky nemocného; průvodce praktického lékaře

MUDr. Pavel Rutar


Med. praxi. 2023;20(3):187-190