Síla křehkosti

Martina Špinková

Med. praxi. 2014;11(6):245  

Vascular disease in menopausal women

doc.MUDr.Michal Vrablík, Ph.D.

Med. praxi. 2014;11(6):249-253  

Epidemiological data clearly show that overall cardiovascular mortality in women exceeds that in the male population. It is after menopause that the woman's risk profile changes rapidly and, due to waning oestrogen production, there occur a number of adverse changes in humoral, cardiovascular, and metabolic regulations, resulting in a steep increase in the overall cardiovascular risk in women. Even long-term vascular risk in postmenopausal women can be reduced by determining the cardiovascular risk as well as actively searching for and intervening with the major risk factors (dyslipidaemia, arterial hypertension, impaired glucose homeostasis,...

Carcinoma of prostate from the General Practitioner point of view

MUDr.Marcel Nesvadba, MBA

Med. praxi. 2014;11(6):254-256  

The care for patients with Carcinoma of prostate is in the hands of the urologists but the essentials knowledgeof the etiopatogenesis, diagnostics and treatment can be useful for every General Practitioners and lead to other cooperation with the specialists.

Ethical and communication aspects of terminal sedation

doc.MUDr.Miroslav Kala, CSc.

Med. praxi. 2014;11(6):266-268  

The aim of the palliative hospice care is to reach the highest possible quality of life of seriously ill patients and to keep their human dignity. Terminal sedation is considered to be an optimal way in cases with intractable patients. This therapeutic approach is full of ethics and has nothing in common with euthanasia. Sufficient enlightening to the patient and his/her family is crucial before starting this therapeutic method. Lack of communication can be a tool that causes misunderstanding and conflicts.

Multiple sclerosis and pregnancy

MUDr.Olga Zapletalová

Med. praxi. 2014;11(6):270-274  

Multiple sclerosis is an autoimmune inflammatory and neurodegenerative disease affecting young women of childbearing age. Owing to the knowledges and modern therapeutic approaches the illness can be really stable and women can carry out their biological role and have children. Maternal immune system undergoes profound transformations at the very beginning of pregnancy. The major changes are directed to protect the fetus from a detrimental immune response and the growing level of pregnancy hormones affects the mother´s immune reactions. According to the results of the clinical trials and long-term clinical experience the pregnancy has positive...

Mild cognitive impairment and dementia syndrome - cognitive function testing

Mgr.Tomáš Nikolai, PhDr.Hana Štěpánková, Ph.D., Mgr.Ondřej Bezdíček, Ph.D.

Med. praxi. 2014;11(6):275-277  

Diagnosing mild cognitive impairment and dementia syndrome has been of increasing importance in recent years in association with population ageing. When determining the degree of cognitive impairment regardless of its aetiology, the diagnostic criteria describing the syndrome of mild cognitive impairment and the dementia syndrome are applicable. Screening methods still play a role in practical diagnosis. They can be used to assess the patient's cognitive status with a certain degree of probability. This article aims at presenting the principles of a clinical screening test for cognition and the utility of selected most widely spread screening...

Care of irritated and senzitive skin

Mgr.Jana Martinásková

Med. praxi. 2014;11(6):279-280  

The article summarizes the current approach to the issue of irritated and sensitive skin. Describes the manifestations of this skin, known causes of irritation and outlines the strategy in the approach of taking care and cure this desease. Given is a list of selected dermocosmetics products with a suitable composition with which is in practice the positive experience.

Doubts about beta-blockers: diabetes mellitus, hypoglycaemia and dyslipidemia

PharmDr.Michal Prokeš, PharmDr.Josef Suchopár

Med. praxi. 2014;11(6):257-264  

Beta-blockers are a heterogenous group of drugs commonly prescribed for the treatment of patients with hypertension, tachyarrhytmias and heart failure. Although prolongation of hypoglycaemia and masking of hypoglycaemia was reported for some beta-blockers, for example propranolol, studies with selective beta-blockers brought conflicting results and population-based studies did not found association between the use of beta-blockres and the risk of hypoglycaemia. An unfavourable metabolic profile of beta-blockers was also reported such as an insuline resistance and dyslipidemia. The evidence is based on studies with weakly-selective or non-selective...

Fixed combination of perindopril and indapamide in patients with renal insufficiency

doc.MUDr.Jitka Seidlerová, Ph.D.

Med. praxi. 2014;11(6):282-283  

Renal insufficiency is a relatively frequent complication or comorbidity in patients with arterial hypertension, particularly in those of older age groups. To achieve target blood pressure levels is of particular importance in these patients. The treatment should be based on a renin-angiotensin system blocker usually in combination with another antihypertensive drug. The article presents a case report of a female patient in whom the use of a fixed combination of perindopril and indapamide resulted in hypertension control, was tolerated very well, and did not result in impaired renal functions.

Co pro léčbu hypertenze znamená příchod první fixní trojkombinace?

MUDr. Martin Vaněk, Ph.D.

Med. praxi. 2014;11(6):264-265  

The economic requirements of development of the health care system of the Czech Republic

Mgr.Lenka Kalábová, Ing.Jana Bellová, Ph.D., Ing.Jaroslav Zlámal, Ph.D.

Med. praxi. 2014;11(6):252-259  

The article deals with the economic requirements of development of the health care system of the Czech Republic in the context of health care as a complex. There are described interconnections between the economic development of the state economy and possibilities of financing the health care. The health care system in the whole extend participates to prevention or restoration of human health and therefor creates an important part of the human wealth fare. In the Czech republic the amount of finances that is distributed to sustain and further develop health care is comparable with the developed European countries, during the last decade the...

Interventional rehabilitation

MUDr.Horák Stanislav, MUDr.Petr Konečný Ph.D., MUDr.Dalibor Pastucha, Mgr.Naděžda Calabová, Mgr.Radka Filipčíková, Ph.D., MUDr.Petr Hubáček, MBA

Med. praxi. 2014;11(6):332-334  

Interventional rehabilitation is a modern approach in the treatment of musculoskeletal disorders where classical conservative physiotherapy fails. It uses the application of the local anesthetic using special anesthetic technique affecting the neuromuscular system. The big advantage is targeted affecting the peripheral nervous system with minimal influence on vital functions and the possibility of cooperation with the patient during the procedure and during rehabilitation. As an example, there is the case of a young man with post-traumatic lower extremity limitations, where the interventional rehabilitation was used with prompt effect.

Léčba infekcí: laboratorní diagnostika má smysl jen při správném odběru racionálních vzorků

Med. praxi. 2014;11(6):284-286