Slovo úvodem

prof. MUDr. Ivan Rektor, CSc.

Med. praxi. 2022;19(2):87 | DOI: 10.36290/med.2022.023  

Celiac Disease in General Practicioner's Outpatient Clinic: diagnosis, treatment and complication

doc. MUDr. Iva Hoffmanová, Ph.D.

Med. praxi. 2022;19(2):92-97 | DOI: 10.36290/med.2022.012  

A review article informes general practitioners of the pathogenesis and clinical presentation of celiac disease (with the emphasis on extraintestinal manifestation), of diagnosis and complication of celiac disease. Screening for celiac disease in risk persons and follow-up of patients are highlighted.

Nocturia - differential diagnosis and treatment

MUDr. Roman Sobotka, FEBU

Med. praxi. 2022;19(2):98-103  

Nocturia has a wide range of causes beyond the urological field. The main causes are polyuria, nocturnal polyuria and disorders of the collection or evacuation function of the bladder. The individual causes must be carefully distinguished from each other with the predominance of non-invasive diagnosis, as the treatment of individual causes of nocturia is diametrically different. If it is not possible to determine exactly the cause of nocturia on the basis of these methods or nocturia does not respond to the specified treatment, it is necessary to proceed to an invasive examination. The treatment of nocturia is based on the diagnosed cause and differs...

Arterial hypertension in adolescents and young adults

prof. MUDr. Tomáš Seeman, CSc., MBA

Med. praxi. 2022;19(2):104-108 | DOI: 10.36290/med.2022.014  

Arterial hypertension is one the most important risk factors for cardiovascular morbidity and mortality in general population of middle and older age beeing present in 30-40% of population. In adolescents and younge people, the prevalence of hypertension is much lower (2-10%), the patients have lower total cardiovascular risk, are being less frequently treated and it takes a longer time to see the benefitial effects of the therapy. Nevertheless, hypertension in young people needs to be diagnosed and treated because it is associated with increased cardiovascular mortality. In all yound patients with hypertension, all necessary investations to reveal...

Patient living with HIV in a general practitioner's outpatient clinic

MUDr. Sam Hofman, doc. MUDr. Dalibor Sedláček, CSc.

Med. praxi. 2022;19(2):109-114 | DOI: 10.36290/med.2022.015  

HIV infection has been known for more than forty years. Over the course of four decades the disease has become in highly adherent patients treatable with a good prognosis, thanks to the tremendous efforts of many teams of scientists from around the world. Its diagnostic has been widely available since the mid-80s. Treatment has gone through many stages of development. Current approaches use combinations of several treatments blocking different sites in the HIV replication cycle. A properly treated patient should be in good clinical condition, the performance of his cellular immunity should be comparable to healthy individuals, and HIV RNA levels should...

Iron intake deficit - nutritional resources, recommended daily allowances, iron supplementation

doc. PharmDr. Miloslav Hronek, Ph.D., PharmDr. Miroslav Kovařík, Ph.D.

Med. praxi. 2022;19(2):119-122 | DOI: 10.36290/med.2022.017  

The review article discusses one of common nutrition deficiencies, iron deficiency, which is the cause of sideropenic anemia. It describes two forms of nutritional sources, the recommended daily allowance of iron and its metabolism in the body. The most common iron preparations are administrated both orally and parenterally, and their correct use is listed.

Extraspinální příčina bolestí zad - subakutní trombóza horní mezenterické žíly

MUDr. Ondřej Krtička, MUDr. Matěj Beneš, MUDr. Petr Pták, Ph.D., MUDr. Svatopluk Ostrý, Ph.D.

Med. praxi. 2022;19(2):123-126 | DOI: 10.36290/med.2022.018  

Superior mesenteric vein trombosis is life-threatening disease due to the risk of mesenteric ischemia. Most common symptoms are abdominal pain, nausea, vomiting and melena or hematochesia. Diagnostic difficulties and delay in diagnosis may be caused by unspecific clinical symptoms. We present case study of patient with subacute superior mesenteric vein trombosis with atypical clinical presentation. Chief complaint of our patient was backpain.

Theophylline - hidden risks

PharmDr. Pavel Čermák, PharmDr. Josef Švéda, PharmDr. Jan Dvořák

Med. praxi. 2022;19(2):127-130 | DOI: 10.36290/med.2022.019  

The possibilities of pharmacotherapeutic alleviation of dyspnoea represent an important topic. When choosing medication a great amount of factors need to be considered with respect to medical condition of a particular patient. One of the well-established bronchodilator drug is a purine analogue theophylline. It is important to remember that this caffeine-related substance may in addition to the positive therapeutic effects (bronchodilator, immunomodulatory) show also some characteristic negative ones such as tachycardia, hypokalaemia, diarrhea, insomnia, convulsions, etc. The article describes a case report of a cardiological patient to whom theophylline...

Lyme disease from the perspective of patients - a qualitative study

Ing. Mgr. Zdeněk Meier, Ph.D., prof. MUDr. Evžen Weigl, CSc., Mgr. Veronika Navrátilová, Mgr. Kristýna Anna Černíková, prof. Ing. Mgr. at Mgr. Peter Tavel, Ph.D.

Med. praxi. 2022;19(2):132-138 | DOI: 10.36290/med.2022.020  

Lyme disease (LB) is the most commonly transmitted tick-borne infection in the Czech Republic. The diagnosis of LB can be complicated. The recommended treatment is antibiotic and usually leads to the disappearance of symptoms and a reduced risk of persistence of Borrelia in the organism. LB does not cause death, but its acute and subsequent symptoms can significantly reduce the quality of life of patients in the long term. The article describes the experience of patients throughout the course of the disease, including the impact of the disease on other aspects of patients' lives. The main output of the research is the publication of the experience...

Pitfalls in the diagnosis of subacute or de Quervain's thyroiditis

doc. MUDr. Milan Halenka, Ph.D.

Med. praxi. 2022;19(2):139-145 | DOI: 10.36290/med.2022.021  

Subacute thyroiditis, also known as de Quervain's thyroiditis, is a painful inflammation of the thyroid gland. The disease is relatively rare and, despite its typical clinical symptoms, laboratory features and ultrasound findings, correct diagnosis is not always quick and easy. It often follows a previous viral infection of the upper respiratory tract. The most common first symptom is palpable and painful thyroid gland accompanied often by symptoms of hyperthyroidism. The disease should be initially distinguished from prolonged upper respiratory tract infection or other causes of thyrotoxicosis and then appropriate therapy should be started. Substantial...

New fixed combination of analgesics

MUDr. Pavlína Nosková, Ph.D.

Med. praxi. 2022;19(2):115-118 | DOI: 10.36290/med.2022.016  

A fixed combination of analgesics in one tablet enhances analgesic efficacy and reduces side effects of the individual components. This expands the portfolio of analgesics to treat acute and chronic pain. Nowadays we have new combination dexketoprofen/tramadol and paracetamol/ibuprofen. The article concludes by describing the practical use of composite analgesics in the treatment of pain.

Moist wound healing for general practitioners - new procedures and legislation

Mgr. Jan Zahálka

Med. praxi. 2022;19(2):146-149 | DOI: 10.36290/med.2022.022  

The article concerns with the development of legal regulations and practical procedures in prescribing medical devices for "moist" wound management in outpatient care and the issue of practical communication with health insurance companies in the matter of reimbursement of these medical devices from public health insurance in the Czech Republic.