Změnila nutriční a metabolická péče tvář moderní intenzivní medicíny?

MUDr. Jan Maňák, Ph.D.

Med. praxi. 2012;9(2):43  

Is prevention of cardiovascular events a question of the treatment chosen?

MUDr.Michal Vrablík, Ph.D.

Med. praxi. 2012;9(2):48-52  

There are increasing options of intervention on risk factors for atherosclerosis (and cardiovascular diseases). However, it is apparent that not all methods of modifying the risk profile have the same effect on the occurrence of clinical episodes. The success of an intervention is determined by correct timing, the decision on the method of treatment, the selection of a particular treatment strategy as well as patient compliance with the proposed strategies. In most clinical settings today, antihypertensive regimens based on a combination of a RAS blocker and a calcium channel blocker usually combined with hypolipidaemic statin treatment are...

Biological therapy of Crohn’s disease

prof.MUDr.Milan Lukáš, CSc.

Med. praxi. 2012;9(2):53-56  

Biologic therapy is the most effective treatment modality in patients with Crohn´s disease. Indications for biological therapy start is moderate or severe Crohn´s disease activity despite of intensive standard therapy. In clinical practice we used immunoglobulins targeted against tumor necrosis factor alpha (TNF-α). Infliximab is a monoclonal, chimeric antibody and adalimumab is a complete human antibody against TNF-α. Biological therapy effectivity is relatively high, more than 80–90 % patients respond due to induction treatment period. Unsolved problem is the secondary treatment failure, which requires a therapy intensification....

What news did occurred in vaccination in 2011?

prof.MUDr.Roman Chlíbek, Ph.D.

Med. praxi. 2012;9(2):57-61  

Number of changes and innovations in the field of vaccination occurred in 2011. Immunization program for children was adapted, the age extension of meningococcal conjugate tetravalent vaccine was registered, revaccination of adolescent by vaccine against mumps was started in some areas, we gained the first experience from the stop of universal vaccination against tuberculosis and from selective BCG vaccination, the mandatory vaccination and inclusion of vaccination against human papillomavirus in the universal immunization program were discussed, the recommendations for vaccination against rotaviruses were created, the adult vaccination calendar...

Vaccination of pregnant women against influenza

MUDr.Daniel Dražan

Med. praxi. 2012;9(2):62-63  

Flu is a very frequent and potentially serious disease affecting individuals of any age. Certain risk factors increase the probability of severe course of flu, complications and even death. Pregnancy belongs to the risk factors. By vaccinating pregnant women we protect two persons with increased risk by one shot: the pregnant woman and her child during its first months after birth. Vaccinating pregnant women against flu is recommended by various medical societies and national and international institutions of public health. Vaccinating pregnant women against flu belongs to important tools of prevention and is not adequately used in the Czech...

Managing acute bronchitis

MUDr.Norbert Pauk, Ph.D.

Med. praxi. 2012;9(2):64-66  

Acute bronchitis is a very frequent diagnosis; however, other acute and chronic respiratory diseases may often be masked by it. Recurrent acute bronchitis should always be a reason for a thorough examination of the respiratory tract including lung function testing. A number of congenital disorders (cystic fibrosis, ciliary dyskinesia, immunodeficiency) can thus be revealed that may have gone undetected in childhood. Common diagnoses after a thorough check-up include early stages of chronic obstructive pulmonary disease (COPD) or bronchial asthma.

Hello, resistance, may I continue? I.

MUDr.Václava Adámková

Med. praxi. 2012;9(2):67-69  

Increasing bacterial resistance to antibiotics is not problem only in hospitals. Multidrug-resistant bacteria are isolated from community-acquired infections as well. Presence of microorganisms, isolated from clinical specimen, frequently reflect patient´s colonization. Rational antibiotic therapy should be safe and effectiveness. Everybody who uses antibiotics is responsible for maintenance of long-term effectiveness.

Diagnosis and treatment of scoliosis

doc.MUDr.Martin Repko, Ph.D.

Med. praxi. 2012;9(2):70-73  

Scoliotic deformity represents serious spinal problem with consequentive affection of the spine as well as cardiopulmonal system. Clinical and imaging examinations are essential parts of the complex examination with x-ray long film and the curve measurement using Cobb angle assignment. Scoliotic curves up to 40 degrees are dedicated for conservative treatment (rehabilitation, orthosis). We indicate scoliotic curves above 40 degrees for surgery. Surgical treatment includes curve correction using implants with spondylodesis by bone grafts. Dispensarization and scoliotic treatment is multidisciplinary.

Erectile dysfunction - diagnosis, new treatment preferences

MUDr.Taťána Šrámková, CSc.

Med. praxi. 2012;9(2):75-78  

Erectile dysfunction is defined as an inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse. Erectile dysfunction (ED) and coronary artery disease (CAD) have the same morphological base – endothelial dysfunction as a first stage of atherosclerosis. ED and CAD have the same risk factors, as a hypertension, dyslipidemia, diabetes mellitus, obesity, age, smoking and sedentary lifestyle. The time interval among the onset ED symptoms and the occurence of CAD symptoms and cardiovascular events is estimated at 2–3 years and 3–5 years respectively. Modern oral form of ED therapy by PDE5 inhibitors...

Gluten-free diet for practice

Mgr.Petra Přibylová

Med. praxi. 2012;9(2):78-81  

Gluten-free diet (GFD) plays a crucial role in the treatment of celiac disease. It is a hereditary autoimmune disease manifested by children and adults with permanent intolerance to gluten in the diet. If we exclude foods containing gluten or its toxic fractions, it is removed the underlying cause. We approach it, even if proven allergy to gluten (rare), its use is controversial in children with ADHD syndrome or autism. The following text will be dealt with on a gluten-free diet only in relation to the treatment of celiac disease. Gluten is a component of the prolamine fraction of proteins that are found together with starch in the endosperm...

Options in wound healing

RNDr.Romana Mrázová, Ph.D., PhDr.Andrea Pokorná, Ph.D., MUDr.Miroslav Krejcar

Med. praxi. 2012;9(2):83-86  

Care for the ill patients with chronic wound is a comprehensive process that requires a multidisciplinary approach and a clear definition of the process steps and their logical consistency and kontinuity. All the steps have to be based of clearly defined competencies and the determination of health workesr responsibilities.

Eruptivní xantomatóza

MUDr. Eva Motyková, MUDr. Michal Vrablík, Ph.D.

Med. praxi. 2012;9(2):82